| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | ethinyl estradiol 9.95 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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76 genes differentially expressed following the CRCGN009_HEPG2_24H:L15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 7.27297 |
| CCL2 | chemokine (C-C motif) ligand 2 | 5.76284 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 4.15316 |
| CHN1 | chimerin 1 | 4.10052 |
| DIPK1A | divergent protein kinase domain 1A | 4.06944 |
| INTS3 | integrator complex subunit 3 | 3.87447 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 3.59991 |
| LCN2 | lipocalin 2 | 3.46547 |
| UBQLN2 | ubiquilin 2 | 3.39874 |
| BLMH | bleomycin hydrolase | 3.36635 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.34731 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.32224 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 3.24313 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.19175 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.15766 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 3.10107 |
| MEF2C | myocyte enhancer factor 2C | 3.01 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 3.00147 |
| H2BC12 | H2B clustered histone 12 | 2.90965 |
| CHMP6 | charged multivesicular body protein 6 | 2.84751 |
| CYCS | cytochrome c, somatic | 2.76369 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 2.70504 |
| MYLK | myosin light chain kinase | 2.64283 |
| BLCAP | bladder cancer associated protein | 2.64066 |
| FPGS | folylpolyglutamate synthase | 2.58792 |
| INPP1 | inositol polyphosphate-1-phosphatase | 2.56788 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.47737 |
| HDGFL3 | HDGF like 3 | 2.46003 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 2.43555 |
| NUCB2 | nucleobindin 2 | 2.34003 |
| ABHD4 | abhydrolase domain containing 4 | 2.32372 |
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 2.31132 |
| ECD | ecdysoneless homolog (Drosophila) | 2.28948 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.23784 |
| CCP110 | centriolar coiled coil protein 110kDa | 2.15914 |
| PARL | presenilin associated, rhomboid-like | 2.15083 |
| FZD1 | frizzled class receptor 1 | 2.13913 |
| ZNHIT6 | zinc finger, HIT-type containing 6 | 2.12834 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.04971 |
| PLSCR1 | phospholipid scramblase 1 | 2.03377 |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A | 2.01994 |
| Symbol | Name | Standardized Value |
|---|---|---|
| OXA1L | oxidase (cytochrome c) assembly 1-like | -6.12961 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -5.70225 |
| HAT1 | histone acetyltransferase 1 | -4.71406 |
| TLCD3A | TLC domain containing 3A | -4.50498 |
| CDK1 | cyclin-dependent kinase 1 | -3.93903 |
| CD320 | CD320 molecule | -3.93625 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -3.83502 |
| RPN1 | ribophorin I | -3.80665 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.80613 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -3.73201 |
| AURKB | aurora kinase B | -3.61635 |
| MELK | maternal embryonic leucine zipper kinase | -3.58475 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.26543 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.24702 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -3.07709 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.99779 |
| PCNA | proliferating cell nuclear antigen | -2.83872 |
| HSPB1 | heat shock 27kDa protein 1 | -2.83694 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | -2.83605 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -2.79884 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.7488 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 | -2.67562 |
| CDC25B | cell division cycle 25B | -2.6047 |
| YME1L1 | YME1-like 1 ATPase | -2.41403 |
| SOAT2 | sterol O-acyltransferase 2 | -2.30469 |
| CCNB1 | cyclin B1 | -2.26368 |
| DCK | deoxycytidine kinase | -2.25884 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -2.24283 |
| ZNF586 | zinc finger protein 586 | -2.10842 |
| HMG20B | high mobility group 20B | -2.09832 |
| HELLS | helicase, lymphoid-specific | -2.09006 |
| PODXL2 | podocalyxin-like 2 | -2.08255 |
| NBPF19 | neuroblastoma breakpoint family, member 19 | -2.07644 |
| CSK | c-src tyrosine kinase | -2.02818 |
| GFER | growth factor, augmenter of liver regeneration | -2.02717 |
