CRCGN009_HEPG2_24H:L17 Gene Set
Genes
46 genes differentially expressed following the CRCGN009_HEPG2_24H:L17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
6.50137
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.9505
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.92981
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.77893
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.65432
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.59928
|
|
STIMATE
|
STIM activating enhancer
|
3.41305
|
|
MYLK
|
myosin light chain kinase
|
3.29426
|
|
CHN1
|
chimerin 1
|
3.22734
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.12044
|
|
CBR3
|
carbonyl reductase 3
|
3.00247
|
|
STK10
|
serine/threonine kinase 10
|
2.95092
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.94632
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.87216
|
|
LCN2
|
lipocalin 2
|
2.83264
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.79318
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.78436
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.70215
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.59952
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
2.59679
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.49891
|
|
MAP7
|
microtubule-associated protein 7
|
2.19415
|
|
PRKCQ
|
protein kinase C, theta
|
2.14018
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.09291
|
|
CYCS
|
cytochrome c, somatic
|
2.06542
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PUF60
|
poly-U binding splicing factor 60KDa
|
-3.78857
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.40695
|
|
CTSD
|
cathepsin D
|
-3.40638
|
|
CCNB2
|
cyclin B2
|
-3.40049
|
|
SNX11
|
sorting nexin 11
|
-3.37601
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.33919
|
|
LDHD
|
lactate dehydrogenase D
|
-3.19199
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.16907
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.03303
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.96209
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.94267
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.84634
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.77269
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-2.4738
|
|
TLR4
|
toll-like receptor 4
|
-2.4492
|
|
PEG10
|
paternally expressed 10
|
-2.39824
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.36695
|
|
RNF167
|
ring finger protein 167
|
-2.34003
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.24219
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.13113
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.05657
|
