| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | chlorphenamine 40.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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57 genes differentially expressed following the CRCGN009_HEPG2_24H:L19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPER1 | G protein-coupled estrogen receptor 1 | 4.60178 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 4.38482 |
| SMIM40 | small integral membrane protein 40 | 4.18118 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 3.52549 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 3.46932 |
| ABHD6 | abhydrolase domain containing 6 | 3.37376 |
| CHN1 | chimerin 1 | 3.16495 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.11937 |
| MOK | MOK protein kinase | 3.11889 |
| LOC122526780 | uncharacterized LOC122526780 | 3.10778 |
| ICAM1 | intercellular adhesion molecule 1 | 2.85873 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 2.67863 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.65641 |
| JADE2 | jade family PHD finger 2 | 2.60805 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.59621 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.50861 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 2.48202 |
| NOSIP | nitric oxide synthase interacting protein | 2.45158 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 2.44345 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.29919 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 2.28595 |
| EPN2 | epsin 2 | 2.21899 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.18903 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 2.12257 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.11496 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.10098 |
| HSPA1A | heat shock 70kDa protein 1A | 2.07923 |
| KLHL9 | kelch-like family member 9 | 2.00088 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -7.49203 |
| GNAS | GNAS complex locus | -5.76379 |
| LDHD | lactate dehydrogenase D | -4.9177 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -4.77224 |
| CCDC86 | coiled-coil domain containing 86 | -4.76153 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.14653 |
| CSK | c-src tyrosine kinase | -3.88327 |
| TLCD3A | TLC domain containing 3A | -3.77052 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.76933 |
| HMG20B | high mobility group 20B | -3.75945 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -3.08548 |
| PCNA | proliferating cell nuclear antigen | -2.92932 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.92672 |
| B4GAT1 | beta-1,4-glucuronyltransferase 1 | -2.7422 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -2.62787 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -2.50071 |
| CCNB2 | cyclin B2 | -2.49579 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -2.35007 |
| ADI1 | acireductone dioxygenase 1 | -2.33818 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | -2.32725 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -2.32154 |
| DSG2 | desmoglein 2 | -2.31974 |
| ISOC1 | isochorismatase domain containing 1 | -2.27143 |
| UGDH | UDP-glucose 6-dehydrogenase | -2.18841 |
| PEG10 | paternally expressed 10 | -2.15728 |
| KYAT3 | kynurenine aminotransferase 3 | -2.07855 |
| RPL27A | ribosomal protein L27a | -2.04857 |
| EGF | epidermal growth factor | -2.01019 |
| RPL3 | ribosomal protein L3 | -2.00969 |
