CRCGN009_HEPG2_24H:L22 Gene Set
Genes
38 genes differentially expressed following the CRCGN009_HEPG2_24H:L22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
5.02832
|
|
MAP7
|
microtubule-associated protein 7
|
4.82033
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
4.52916
|
|
CCNA1
|
cyclin A1
|
3.94452
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.87469
|
|
EPN2
|
epsin 2
|
3.84557
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.72403
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.71577
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.34657
|
|
RRAGA
|
Ras-related GTP binding A
|
3.06286
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
3.05544
|
|
ZNF589
|
zinc finger protein 589
|
2.94382
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.87528
|
|
CYB561
|
cytochrome b561
|
2.51396
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.48847
|
|
PLCB3
|
phospholipase C, beta 3 (phosphatidylinositol-specific)
|
2.3349
|
|
KIF20A
|
kinesin family member 20A
|
2.22315
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
2.16744
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.08266
|
|
CRTAP
|
cartilage associated protein
|
2.03267
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ADI1
|
acireductone dioxygenase 1
|
-6.66128
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-5.94286
|
|
VAT1
|
vesicle amine transport 1
|
-5.31715
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.01375
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.9644
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.82128
|
|
ZW10
|
zw10 kinetochore protein
|
-4.10939
|
|
TLR4
|
toll-like receptor 4
|
-3.96366
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.762
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.625
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.12424
|
|
CSK
|
c-src tyrosine kinase
|
-2.81197
|
|
CCNB2
|
cyclin B2
|
-2.59187
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.43128
|
|
HYOU1
|
hypoxia up-regulated 1
|
-2.25974
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.21574
|
|
AKAP8
|
A kinase (PRKA) anchor protein 8
|
-2.08776
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.07988
|
