CRCGN009_HEPG2_24H:L23 Gene Set
Genes
49 genes differentially expressed following the CRCGN009_HEPG2_24H:L23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
10.0
|
|
CHMP6
|
charged multivesicular body protein 6
|
6.95234
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
6.05044
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.40743
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
3.27822
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.05519
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.02406
|
|
NOTCH1
|
notch 1
|
2.91592
|
|
MEST
|
mesoderm specific transcript
|
2.73844
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.6766
|
|
DDX60
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
|
2.6695
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.61812
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.5374
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.50444
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
2.46163
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.38349
|
|
TATDN2
|
TatD DNase domain containing 2
|
2.38074
|
|
LCN2
|
lipocalin 2
|
2.3147
|
|
PMM2
|
phosphomannomutase 2
|
2.31177
|
|
ERI2
|
ERI1 exoribonuclease family member 2
|
2.2188
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.09949
|
|
IFIT1
|
interferon-induced protein with tetratricopeptide repeats 1
|
2.05856
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.04989
|
|
ISG15
|
ISG15 ubiquitin-like modifier
|
2.01978
|
|
PIH1D1
|
PIH1 domain containing 1
|
2.01921
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.00318
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GNAS
|
GNAS complex locus
|
-7.47084
|
|
TLR4
|
toll-like receptor 4
|
-6.05146
|
|
COG4
|
component of oligomeric golgi complex 4
|
-5.64497
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-5.09205
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-3.47781
|
|
CSK
|
c-src tyrosine kinase
|
-3.45159
|
|
LDHD
|
lactate dehydrogenase D
|
-3.05116
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.98028
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.85777
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.77508
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.74458
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.42926
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.41603
|
|
RNF167
|
ring finger protein 167
|
-2.3915
|
|
PABPC1
|
poly(A) binding protein, cytoplasmic 1
|
-2.21185
|
|
SPANXB1
|
SPANX family, member B1
|
-2.13435
|
|
RNF130
|
ring finger protein 130
|
-2.124
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.11835
|
|
TRAP1
|
TNF receptor-associated protein 1
|
-2.10415
|
|
LPA
|
lipoprotein, Lp(a)
|
-2.07468
|
|
GYS2
|
glycogen synthase 2 (liver)
|
-2.07331
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.06959
|
|
CNKSR3
|
CNKSR family member 3
|
-2.02882
|
