CRCGN009_HEPG2_24H:M01 Gene Set
Genes
40 genes differentially expressed following the CRCGN009_HEPG2_24H:M01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HOXA10
|
homeobox A10
|
5.88441
|
|
PRR15L
|
proline rich 15-like
|
5.64003
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
5.58623
|
|
CYCS
|
cytochrome c, somatic
|
5.41262
|
|
LCN2
|
lipocalin 2
|
5.30576
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
5.24705
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.06706
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.84998
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.74938
|
|
UBQLN2
|
ubiquilin 2
|
4.52772
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.851
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.74077
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
3.32985
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
3.11822
|
|
KIF5C
|
kinesin family member 5C
|
2.99411
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.95495
|
|
RRAGA
|
Ras-related GTP binding A
|
2.90375
|
|
NOTCH1
|
notch 1
|
2.82425
|
|
KIF20A
|
kinesin family member 20A
|
2.42782
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.38937
|
|
CBR1
|
carbonyl reductase 1
|
2.20913
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.168
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-5.24019
|
|
CDC20
|
cell division cycle 20
|
-5.00431
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-4.92966
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.84936
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.80923
|
|
YME1L1
|
YME1-like 1 ATPase
|
-3.78577
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-3.45963
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.34764
|
|
PLK1
|
polo-like kinase 1
|
-3.31863
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.16079
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.95982
|
|
CDC25B
|
cell division cycle 25B
|
-2.63303
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.54205
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.53256
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.40586
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.28033
|
|
NFKBIA
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
|
-2.25863
|
|
TPBG
|
trophoblast glycoprotein
|
-2.15489
|
