| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | di(2-ethylhexyl)phthalate 20.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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58 genes differentially expressed following the CRCGN009_HEPG2_24H:M02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 8.70049 |
| STIMATE | STIM activating enhancer | 7.46955 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 6.84537 |
| AMDHD2 | amidohydrolase domain containing 2 | 4.80848 |
| NOTCH1 | notch 1 | 4.73271 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 4.70805 |
| UBQLN2 | ubiquilin 2 | 4.70375 |
| CHMP6 | charged multivesicular body protein 6 | 4.48018 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.46318 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.98518 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.57211 |
| SNX7 | sorting nexin 7 | 3.16712 |
| GATA3 | GATA binding protein 3 | 3.09 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) | 2.96321 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 2.95328 |
| EGF | epidermal growth factor | 2.68221 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 2.66965 |
| RPL39L | ribosomal protein L39-like | 2.51442 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.48514 |
| ATP11B | ATPase, class VI, type 11B | 2.40888 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 2.39015 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.34466 |
| CDK19 | cyclin-dependent kinase 19 | 2.30038 |
| CCNF | cyclin F | 2.24581 |
| BIRC7 | baculoviral IAP repeat containing 7 | 2.16152 |
| APOBEC3F | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F | 2.14664 |
| NOSIP | nitric oxide synthase interacting protein | 2.13608 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.05837 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.04617 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 2.00081 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -5.52301 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -5.51899 |
| HEATR1 | HEAT repeat containing 1 | -5.47552 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -4.93981 |
| ANKRD10 | ankyrin repeat domain 10 | -4.66554 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.47185 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -4.28574 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.02517 |
| DUSP6 | dual specificity phosphatase 6 | -3.55293 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.37895 |
| TLR4 | toll-like receptor 4 | -3.31561 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -3.11882 |
| LAP3 | leucine aminopeptidase 3 | -3.08557 |
| GNAS | GNAS complex locus | -3.05123 |
| HMG20B | high mobility group 20B | -2.9554 |
| PCNA | proliferating cell nuclear antigen | -2.94712 |
| SCAND1 | SCAN domain containing 1 | -2.94609 |
| ZNF586 | zinc finger protein 586 | -2.92802 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.77902 |
| FAIM | Fas apoptotic inhibitory molecule | -2.64879 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.62034 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -2.55953 |
| EIF5 | eukaryotic translation initiation factor 5 | -2.49908 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.44731 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.2013 |
| PLEKHJ1 | pleckstrin homology domain containing, family J member 1 | -2.14117 |
| LDHD | lactate dehydrogenase D | -2.1222 |
| CSK | c-src tyrosine kinase | -2.02625 |
