CRCGN009_HEPG2_24H:M07 Gene Set
Genes
49 genes differentially expressed following the CRCGN009_HEPG2_24H:M07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
6.74664
|
|
CHMP6
|
charged multivesicular body protein 6
|
6.68179
|
|
UBQLN2
|
ubiquilin 2
|
6.6179
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
4.12614
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
3.87449
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
3.79411
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.28255
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
3.0775
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
3.07537
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.05337
|
|
MEST
|
mesoderm specific transcript
|
2.93664
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
2.84874
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.50211
|
|
TXNRD1
|
thioredoxin reductase 1
|
2.33515
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.30289
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.23592
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
2.12993
|
|
ALAS1
|
5'-aminolevulinate synthase 1
|
2.08284
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.07559
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
2.0362
|
|
CHN1
|
chimerin 1
|
2.02072
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-9.78901
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-5.94555
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.57713
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.37909
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-4.07181
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.01214
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.95805
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.89125
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.85652
|
|
HMG20B
|
high mobility group 20B
|
-3.80208
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.6113
|
|
CDC20
|
cell division cycle 20
|
-3.52123
|
|
TLR4
|
toll-like receptor 4
|
-3.07214
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.85618
|
|
VAT1
|
vesicle amine transport 1
|
-2.82308
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.80246
|
|
AURKA
|
aurora kinase A
|
-2.75934
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.75926
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.67569
|
|
SCAND1
|
SCAN domain containing 1
|
-2.6644
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-2.65873
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.56843
|
|
LDHD
|
lactate dehydrogenase D
|
-2.33675
|
|
CDC25B
|
cell division cycle 25B
|
-2.25673
|
|
CCNH
|
cyclin H
|
-2.14987
|
|
ID2
|
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
|
-2.09261
|
|
GNAS
|
GNAS complex locus
|
-2.0753
|
|
AKAP8
|
A kinase (PRKA) anchor protein 8
|
-2.0661
|
