CRCGN009_HEPG2_24H:M09 Gene Set
Genes
48 genes differentially expressed following the CRCGN009_HEPG2_24H:M09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
6.38376
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.25768
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
5.79904
|
|
ATP11B
|
ATPase, class VI, type 11B
|
4.36365
|
|
RPL39L
|
ribosomal protein L39-like
|
4.09697
|
|
STIMATE
|
STIM activating enhancer
|
3.70173
|
|
LCN2
|
lipocalin 2
|
3.69627
|
|
BLMH
|
bleomycin hydrolase
|
3.63244
|
|
UBQLN2
|
ubiquilin 2
|
3.62649
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.33814
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.30152
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
3.02685
|
|
EAPP
|
E2F-associated phosphoprotein
|
2.92769
|
|
MYLK
|
myosin light chain kinase
|
2.68333
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.51576
|
|
CHEK2
|
checkpoint kinase 2
|
2.37706
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.27739
|
|
MCM3
|
minichromosome maintenance complex component 3
|
2.18434
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.14269
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.08086
|
|
EVL
|
Enah/Vasp-like
|
2.00007
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-5.97548
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.96384
|
|
CCNB2
|
cyclin B2
|
-5.29986
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.49847
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.65074
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.52324
|
|
PLK1
|
polo-like kinase 1
|
-3.4352
|
|
CD320
|
CD320 molecule
|
-3.21961
|
|
DNM1L
|
dynamin 1-like
|
-2.96426
|
|
HYOU1
|
hypoxia up-regulated 1
|
-2.93058
|
|
SCAND1
|
SCAN domain containing 1
|
-2.60508
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.58177
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.57415
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.42069
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-2.3347
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.32437
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.32237
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.26712
|
|
LDHD
|
lactate dehydrogenase D
|
-2.24734
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.20371
|
|
NCK2
|
NCK adaptor protein 2
|
-2.18056
|
|
HMG20B
|
high mobility group 20B
|
-2.1537
|
|
TLR4
|
toll-like receptor 4
|
-2.15141
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.14744
|
|
PDE8B
|
phosphodiesterase 8B
|
-2.09547
|
|
RASIP1
|
Ras interacting protein 1
|
-2.04766
|
|
SECISBP2
|
SECIS binding protein 2
|
-2.00144
|
