| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | hydrazobenzene 5.05 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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49 genes differentially expressed following the CRCGN009_HEPG2_24H:M10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GSTZ1 | glutathione S-transferase zeta 1 | 6.35301 |
| ABHD6 | abhydrolase domain containing 6 | 5.34133 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 4.65149 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 4.0953 |
| CHMP6 | charged multivesicular body protein 6 | 3.79687 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 3.69344 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.48396 |
| ADRB2 | adrenoceptor beta 2, surface | 3.45447 |
| CTSL | cathepsin L | 3.08757 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 3.08575 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 2.9109 |
| CYCS | cytochrome c, somatic | 2.8912 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.86674 |
| PRKCH | protein kinase C, eta | 2.82398 |
| DIPK1A | divergent protein kinase domain 1A | 2.65655 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.52406 |
| NOSIP | nitric oxide synthase interacting protein | 2.46302 |
| UFM1 | ubiquitin-fold modifier 1 | 2.39141 |
| EGF | epidermal growth factor | 2.35367 |
| CEP57 | centrosomal protein 57kDa | 2.31518 |
| TK1 | thymidine kinase 1, soluble | 2.24773 |
| LRRC20 | leucine rich repeat containing 20 | 2.24272 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.22565 |
| E2F2 | E2F transcription factor 2 | 2.19807 |
| PKN1 | protein kinase N1 | 2.17652 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.06594 |
| AAMDC | adipogenesis associated, Mth938 domain containing | 2.04967 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.04073 |
| BCL9 | B-cell CLL/lymphoma 9 | 2.01896 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -7.06776 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -6.70673 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.82147 |
| TLR4 | toll-like receptor 4 | -5.30355 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -5.18687 |
| TRIB3 | tribbles pseudokinase 3 | -3.91469 |
| CDC20 | cell division cycle 20 | -3.8902 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.86412 |
| GTPBP8 | GTP-binding protein 8 (putative) | -3.72176 |
| CHMP4B | charged multivesicular body protein 4B | -3.64185 |
| SMNDC1 | survival motor neuron domain containing 1 | -3.10841 |
| CCNB1 | cyclin B1 | -2.91057 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.8696 |
| TSPAN4 | tetraspanin 4 | -2.86876 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.76731 |
| BLVRA | biliverdin reductase A | -2.71213 |
| LOC124907782 | dual specificity protein phosphatase 22 | -2.65824 |
| GNAS | GNAS complex locus | -2.41243 |
| CCL8 | chemokine (C-C motif) ligand 8 | -2.08662 |
| H1-2 | H1.2 linker histone, cluster member | -2.07345 |
