CRCGN009_HEPG2_24H:M11 Gene Set
Genes
47 genes differentially expressed following the CRCGN009_HEPG2_24H:M11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.74192
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.31623
|
|
HOXA10
|
homeobox A10
|
4.24029
|
|
CBR3
|
carbonyl reductase 3
|
3.60908
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.18683
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.87018
|
|
CCNF
|
cyclin F
|
2.78627
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.7764
|
|
ZFP30
|
ZFP30 zinc finger protein
|
2.64744
|
|
GPATCH8
|
G patch domain containing 8
|
2.59417
|
|
CHN1
|
chimerin 1
|
2.51334
|
|
NAALADL1
|
N-acetylated alpha-linked acidic dipeptidase-like 1
|
2.48079
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.43038
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.28571
|
|
RAB31
|
RAB31, member RAS oncogene family
|
2.28489
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
2.21318
|
|
ZNF432
|
zinc finger protein 432
|
2.18619
|
|
PRKCH
|
protein kinase C, eta
|
2.04416
|
|
HOXA10-HOXA9
|
HOXA10-HOXA9 readthrough
|
2.04225
|
|
INSIG2
|
insulin induced gene 2
|
2.03242
|
|
GBP2
|
guanylate binding protein 2, interferon-inducible
|
2.02413
|
|
FER
|
fer (fps/fes related) tyrosine kinase
|
2.01333
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.83792
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.52664
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.69348
|
|
CSK
|
c-src tyrosine kinase
|
-3.55086
|
|
VAT1
|
vesicle amine transport 1
|
-3.45504
|
|
EGF
|
epidermal growth factor
|
-3.19938
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.17203
|
|
CDC25B
|
cell division cycle 25B
|
-3.08787
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.06228
|
|
SNX11
|
sorting nexin 11
|
-3.03806
|
|
THAP11
|
THAP domain containing 11
|
-2.77607
|
|
CDC20
|
cell division cycle 20
|
-2.73196
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.7006
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.58965
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.56503
|
|
SESN1
|
sestrin 1
|
-2.41398
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.40502
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.39725
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.38944
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-2.33745
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
-2.33715
|
|
CCNB2
|
cyclin B2
|
-2.15037
|
|
GNAS
|
GNAS complex locus
|
-2.13707
|
|
TUBB4A
|
tubulin, beta 4A class IVa
|
-2.08449
|
