CRCGN009_HEPG2_24H:M16 Gene Set
Genes
48 genes differentially expressed following the CRCGN009_HEPG2_24H:M16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
6.67873
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
6.17816
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
5.11165
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.15567
|
|
LCN2
|
lipocalin 2
|
3.79935
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
3.37944
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.09623
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.01394
|
|
STK10
|
serine/threonine kinase 10
|
2.83914
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.58428
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
2.58015
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
2.57157
|
|
CYCS
|
cytochrome c, somatic
|
2.53758
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.50049
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.4458
|
|
RAB11FIP2
|
RAB11 family interacting protein 2 (class I)
|
2.38433
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
2.34818
|
|
EIF4EBP1
|
eukaryotic translation initiation factor 4E binding protein 1
|
2.30621
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.2196
|
|
GATA2
|
GATA binding protein 2
|
2.1958
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
2.18642
|
|
NOTCH1
|
notch 1
|
2.18071
|
|
TRIM13
|
tripartite motif containing 13
|
2.16133
|
|
ARPC1B
|
actin related protein 2/3 complex, subunit 1B, 41kDa
|
2.13163
|
|
H2BC12
|
H2B clustered histone 12
|
2.0395
|
|
TXNRD1
|
thioredoxin reductase 1
|
2.018
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-6.22543
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.98455
|
|
CCNB2
|
cyclin B2
|
-4.86997
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.96954
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.9305
|
|
TIMM9
|
translocase of inner mitochondrial membrane 9 homolog (yeast)
|
-3.88992
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.79769
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.57458
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.32761
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.29109
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.19572
|
|
CCNB1
|
cyclin B1
|
-2.63359
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.62309
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.59833
|
|
HMG20B
|
high mobility group 20B
|
-2.46734
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.4422
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
-2.38942
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.38143
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.28376
|
|
VAT1
|
vesicle amine transport 1
|
-2.25795
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.17929
|
|
TACO1
|
translational activator of mitochondrially encoded cytochrome c oxidase I
|
-2.09682
|
