CRCGN009_HEPG2_24H:M17 Gene Set
Genes
35 genes differentially expressed following the CRCGN009_HEPG2_24H:M17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
8.04934
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
6.02308
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.19277
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
5.01413
|
|
HEBP1
|
heme binding protein 1
|
4.15264
|
|
HOXA10
|
homeobox A10
|
3.56162
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.98525
|
|
MOK
|
MOK protein kinase
|
2.80932
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.62832
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.61703
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.58634
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
2.58602
|
|
CCNF
|
cyclin F
|
2.54288
|
|
STK10
|
serine/threonine kinase 10
|
2.48304
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.37069
|
|
CETN3
|
centrin, EF-hand protein, 3
|
2.18339
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.0954
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.05043
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.8429
|
|
COG7
|
component of oligomeric golgi complex 7
|
-5.20568
|
|
CDC20
|
cell division cycle 20
|
-5.17441
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.98147
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.8118
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.79107
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.76257
|
|
TLR4
|
toll-like receptor 4
|
-3.48
|
|
MACF1
|
microtubule-actin crosslinking factor 1
|
-3.20149
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.00018
|
|
SNX11
|
sorting nexin 11
|
-2.87648
|
|
MVP
|
major vault protein
|
-2.86583
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.52233
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
-2.39764
|
|
TBCC
|
tubulin folding cofactor C
|
-2.30491
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.27814
|
|
ABCF3
|
ATP-binding cassette, sub-family F (GCN20), member 3
|
-2.19015
|
