| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | [1,1'-biphenyl]-3,3',4,4'-tetramine tetrahydrochloride 0.62 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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63 genes differentially expressed following the CRCGN009_HEPG2_24H:M18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 8.65074 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 5.55079 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 5.11035 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 4.53855 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.50449 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 4.49821 |
| MYLK | myosin light chain kinase | 4.43456 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 4.38915 |
| CYCS | cytochrome c, somatic | 4.16314 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.05823 |
| CBR3 | carbonyl reductase 3 | 3.99587 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 3.9799 |
| NOTCH1 | notch 1 | 3.97938 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.93463 |
| LOC122526780 | uncharacterized LOC122526780 | 3.19424 |
| CHN1 | chimerin 1 | 2.86274 |
| NOSIP | nitric oxide synthase interacting protein | 2.8288 |
| HEBP1 | heme binding protein 1 | 2.63869 |
| JUN | jun proto-oncogene | 2.57994 |
| PTK2 | protein tyrosine kinase 2 | 2.53271 |
| ZNF589 | zinc finger protein 589 | 2.52852 |
| TBXA2R | thromboxane A2 receptor | 2.29796 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) | 2.26 |
| NBPF3 | neuroblastoma breakpoint family, member 3 | 2.23208 |
| GYS1 | glycogen synthase 1 (muscle) | 2.1645 |
| SUOX | sulfite oxidase | 2.14735 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.13825 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | 2.13164 |
| GPATCH8 | G patch domain containing 8 | 2.12629 |
| PARL | presenilin associated, rhomboid-like | 2.10181 |
| FAM111A | family with sequence similarity 111, member A | 2.09627 |
| RAP2C | RAP2C, member of RAS oncogene family | 2.08225 |
| RTRAF | RNA transcription, translation and transport factor | 2.06107 |
| MGA | MGA, MAX dimerization protein | 2.04584 |
| GOLM1 | golgi membrane protein 1 | 2.03254 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -8.41757 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -5.83638 |
| PCNA | proliferating cell nuclear antigen | -5.46574 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -4.66511 |
| UGDH | UDP-glucose 6-dehydrogenase | -4.62923 |
| GOLT1B | golgi transport 1B | -4.59915 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -4.59621 |
| CSK | c-src tyrosine kinase | -4.43726 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.24304 |
| UBE3C | ubiquitin protein ligase E3C | -4.23841 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.21929 |
| LDHD | lactate dehydrogenase D | -4.21592 |
| CDC20 | cell division cycle 20 | -4.17406 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | -4.06271 |
| NRIP1 | nuclear receptor interacting protein 1 | -3.91393 |
| RPN1 | ribophorin I | -3.80126 |
| TOMM70 | translocase of outer mitochondrial membrane 70 | -2.63939 |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 | -2.50271 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.33678 |
| GLOD4 | glyoxalase domain containing 4 | -2.18902 |
| RBM15B | RNA binding motif protein 15B | -2.12005 |
| PYGB | phosphorylase, glycogen; brain | -2.0846 |
| CBR4 | carbonyl reductase 4 | -2.03591 |
| TMEM165 | transmembrane protein 165 | -2.01925 |
| AAGAB | alpha- and gamma-adaptin binding protein | -2.01268 |
| HMG20A | high mobility group 20A | -2.01156 |
| NEO1 | neogenin 1 | -2.00859 |
| SIL1 | SIL1 nucleotide exchange factor | -2.00832 |
