CRCGN009_HEPG2_24H:M21 Gene Set
Genes
48 genes differentially expressed following the CRCGN009_HEPG2_24H:M21 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHMP6
|
charged multivesicular body protein 6
|
6.64183
|
|
MAP7
|
microtubule-associated protein 7
|
4.87313
|
|
INTS3
|
integrator complex subunit 3
|
3.79014
|
|
UBQLN2
|
ubiquilin 2
|
3.62399
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.57857
|
|
GATA2
|
GATA binding protein 2
|
3.4136
|
|
LCN2
|
lipocalin 2
|
3.37934
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.29289
|
|
CYCS
|
cytochrome c, somatic
|
3.0865
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.05712
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.99699
|
|
SFTPB
|
surfactant protein B
|
2.82081
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.63897
|
|
INPP1
|
inositol polyphosphate-1-phosphatase
|
2.44134
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.34956
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.27324
|
|
CHAC1
|
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
|
2.18173
|
|
OR1F1
|
olfactory receptor, family 1, subfamily F, member 1
|
2.11775
|
|
ICAM1
|
intercellular adhesion molecule 1
|
2.07696
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.06646
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-10.0
|
|
DNM1L
|
dynamin 1-like
|
-6.58143
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-5.34088
|
|
TLR4
|
toll-like receptor 4
|
-4.33028
|
|
BLCAP
|
bladder cancer associated protein
|
-3.98209
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-3.6834
|
|
CDC20
|
cell division cycle 20
|
-3.39909
|
|
LDHD
|
lactate dehydrogenase D
|
-3.19076
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-3.15756
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.01188
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-2.9253
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.90002
|
|
CDC25B
|
cell division cycle 25B
|
-2.7725
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-2.70598
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.67513
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.66362
|
|
RNF167
|
ring finger protein 167
|
-2.62842
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.58847
|
|
CAB39
|
calcium binding protein 39
|
-2.46225
|
|
ZNF586
|
zinc finger protein 586
|
-2.41602
|
|
MIDEAS
|
mitotic deacetylase associated SANT domain protein
|
-2.33713
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.19669
|
|
CCNB2
|
cyclin B2
|
-2.17514
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-2.09107
|
|
ERC2
|
ELKS/RAB6-interacting/CAST family member 2
|
-2.07081
|
|
HYOU1
|
hypoxia up-regulated 1
|
-2.04991
|
|
SNX11
|
sorting nexin 11
|
-2.02366
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.0171
|
