CRCGN009_HEPG2_24H:M22 Gene Set
Genes
51 genes differentially expressed following the CRCGN009_HEPG2_24H:M22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CYCS
|
cytochrome c, somatic
|
7.46929
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
6.13672
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
4.31213
|
|
SUV39H1
|
suppressor of variegation 3-9 homolog 1 (Drosophila)
|
4.15169
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.12651
|
|
UBQLN2
|
ubiquilin 2
|
3.84492
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
3.62798
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.44696
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
3.31136
|
|
MYLK
|
myosin light chain kinase
|
3.21814
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.20258
|
|
SQOR
|
sulfide quinone oxidoreductase
|
3.16263
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
3.0076
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.68147
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.67836
|
|
HOXA10
|
homeobox A10
|
2.59919
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.41814
|
|
NPDC1
|
neural proliferation, differentiation and control, 1
|
2.41405
|
|
MICALL1
|
MICAL-like 1
|
2.409
|
|
VPS28
|
vacuolar protein sorting 28 homolog (S. cerevisiae)
|
2.32542
|
|
HEBP1
|
heme binding protein 1
|
2.27053
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
2.08388
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.04095
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.03903
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.01024
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCDC86
|
coiled-coil domain containing 86
|
-6.5724
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-5.85335
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.66764
|
|
GNAS
|
GNAS complex locus
|
-5.44908
|
|
THAP11
|
THAP domain containing 11
|
-4.18612
|
|
ZNF586
|
zinc finger protein 586
|
-3.4503
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.32644
|
|
RPN1
|
ribophorin I
|
-3.23037
|
|
SCAND1
|
SCAN domain containing 1
|
-3.11529
|
|
SLC35A1
|
solute carrier family 35 (CMP-sialic acid transporter), member A1
|
-3.03899
|
|
LDHD
|
lactate dehydrogenase D
|
-2.74832
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.5724
|
|
TLR4
|
toll-like receptor 4
|
-2.52129
|
|
FHL2
|
four and a half LIM domains 2
|
-2.47734
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.45001
|
|
EGF
|
epidermal growth factor
|
-2.32579
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.17768
|
|
NUTF2
|
nuclear transport factor 2
|
-2.17354
|
|
NLGN4Y
|
neuroligin 4, Y-linked
|
-2.11454
|
|
TRAP1
|
TNF receptor-associated protein 1
|
-2.09902
|
|
HAGH
|
hydroxyacylglutathione hydrolase
|
-2.08343
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-2.06776
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
-2.06369
|
|
ABCF3
|
ATP-binding cassette, sub-family F (GCN20), member 3
|
-2.05343
|
|
ARHGEF26
|
Rho guanine nucleotide exchange factor (GEF) 26
|
-2.04738
|
|
HSPA8
|
heat shock 70kDa protein 8
|
-2.04626
|
