CRCGN009_HEPG2_24H:M23 Gene Set
Genes
59 genes differentially expressed following the CRCGN009_HEPG2_24H:M23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHMP6
|
charged multivesicular body protein 6
|
6.39125
|
|
MAP7
|
microtubule-associated protein 7
|
6.17596
|
|
MYLK
|
myosin light chain kinase
|
4.02841
|
|
CYCS
|
cytochrome c, somatic
|
4.01887
|
|
NUP133
|
nucleoporin 133kDa
|
3.94268
|
|
NOTCH1
|
notch 1
|
3.89595
|
|
CHN1
|
chimerin 1
|
3.79674
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
3.7001
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.54765
|
|
KLHL9
|
kelch-like family member 9
|
3.49295
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.44067
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.33883
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.33411
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.94925
|
|
GATA2
|
GATA binding protein 2
|
2.93615
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.73587
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.70189
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
2.36473
|
|
UPB1
|
ureidopropionase, beta
|
2.17085
|
|
MCTP1
|
multiple C2 domains, transmembrane 1
|
2.16287
|
|
SLC10A2
|
solute carrier family 10 (sodium/bile acid cotransporter), member 2
|
2.15576
|
|
CCNF
|
cyclin F
|
2.14547
|
|
RBKS
|
ribokinase
|
2.13107
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.11553
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
2.10848
|
|
E2F2
|
E2F transcription factor 2
|
2.08639
|
|
TTC38
|
tetratricopeptide repeat domain 38
|
2.04224
|
|
PMM2
|
phosphomannomutase 2
|
2.03099
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-7.71433
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.47308
|
|
IDH1
|
isocitrate dehydrogenase 1 (NADP+), soluble
|
-5.54218
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.86865
|
|
ZNF586
|
zinc finger protein 586
|
-4.81149
|
|
GNAS
|
GNAS complex locus
|
-4.56979
|
|
CCNB2
|
cyclin B2
|
-4.26384
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.22823
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-4.16084
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-4.12117
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.07147
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.06536
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.87847
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.64523
|
|
NISCH
|
nischarin
|
-3.58712
|
|
COG7
|
component of oligomeric golgi complex 7
|
-3.48524
|
|
HMG20B
|
high mobility group 20B
|
-2.82426
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.82398
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.7497
|
|
UBFD1
|
ubiquitin family domain containing 1
|
-2.49365
|
|
RNF167
|
ring finger protein 167
|
-2.39646
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.37453
|
|
CCNB1
|
cyclin B1
|
-2.3495
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.30536
|
|
EGF
|
epidermal growth factor
|
-2.26315
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.263
|
|
CTNND1
|
catenin (cadherin-associated protein), delta 1
|
-2.25496
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-2.19512
|
|
PRKRIP1
|
PRKR interacting protein 1 (IL11 inducible)
|
-2.10302
|
|
CSK
|
c-src tyrosine kinase
|
-2.02034
|
|
PEG10
|
paternally expressed 10
|
-2.00644
|
