CRCGN009_HEPG2_24H:M24 Gene Set
Genes
46 genes differentially expressed following the CRCGN009_HEPG2_24H:M24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
6.95225
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
6.40813
|
|
LCN2
|
lipocalin 2
|
4.81357
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
4.42117
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.25976
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.58144
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.52812
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.46433
|
|
CBR3
|
carbonyl reductase 3
|
3.40778
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.23655
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.22557
|
|
STK10
|
serine/threonine kinase 10
|
3.2099
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.77033
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.69279
|
|
MAP7
|
microtubule-associated protein 7
|
2.60532
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.35444
|
|
CYCS
|
cytochrome c, somatic
|
2.29553
|
|
AXIN1
|
axin 1
|
2.24852
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
2.21791
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.19033
|
|
ARID4B
|
AT rich interactive domain 4B (RBP1-like)
|
2.14546
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.12626
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC20
|
cell division cycle 20
|
-6.9586
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-6.84341
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.93247
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.96278
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.23494
|
|
FASTKD5
|
FAST kinase domains 5
|
-3.82489
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.6996
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.5701
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.48171
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.3056
|
|
EGF
|
epidermal growth factor
|
-3.09142
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.90047
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.8955
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.87554
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.85048
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-2.81233
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.71784
|
|
TLR4
|
toll-like receptor 4
|
-2.70824
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.48537
|
|
CD320
|
CD320 molecule
|
-2.39315
|
|
SNX11
|
sorting nexin 11
|
-2.307
|
|
MTA1
|
metastasis associated 1
|
-2.04786
|
|
HSD11B1
|
hydroxysteroid (11-beta) dehydrogenase 1
|
-2.03391
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.02879
|
