CRCGN009_HEPG2_24H:N01 Gene Set
Genes
41 genes differentially expressed following the CRCGN009_HEPG2_24H:N01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
MAP7
|
microtubule-associated protein 7
|
4.72823
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.98113
|
|
E2F2
|
E2F transcription factor 2
|
3.97233
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.93603
|
|
CBR3
|
carbonyl reductase 3
|
3.75082
|
|
HEBP1
|
heme binding protein 1
|
3.72322
|
|
BLMH
|
bleomycin hydrolase
|
3.57745
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.5063
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.42255
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.64555
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.59009
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.57228
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.4245
|
|
STXBP1
|
syntaxin binding protein 1
|
2.34607
|
|
SORBS3
|
sorbin and SH3 domain containing 3
|
2.25978
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
2.25805
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.23644
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.13411
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.13382
|
|
CYCS
|
cytochrome c, somatic
|
2.09294
|
|
PRSS3
|
protease, serine, 3
|
2.02423
|
|
CCNF
|
cyclin F
|
2.00459
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-5.16223
|
|
TLR4
|
toll-like receptor 4
|
-4.51163
|
|
LDHD
|
lactate dehydrogenase D
|
-3.93001
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.64513
|
|
ZNF586
|
zinc finger protein 586
|
-3.63212
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.4449
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.38031
|
|
CSK
|
c-src tyrosine kinase
|
-2.73282
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.60007
|
|
ERC2
|
ELKS/RAB6-interacting/CAST family member 2
|
-2.55052
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.51895
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.49404
|
|
RPS5
|
ribosomal protein S5
|
-2.35295
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.31759
|
|
BDH1
|
3-hydroxybutyrate dehydrogenase, type 1
|
-2.15594
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.12959
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.11298
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.09617
|
|
ILK
|
integrin-linked kinase
|
-2.03534
|
