CRCGN009_HEPG2_24H:N06 Gene Set
Genes
45 genes differentially expressed following the CRCGN009_HEPG2_24H:N06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
7.46869
|
|
STK10
|
serine/threonine kinase 10
|
5.96852
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
5.93242
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.93673
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.90437
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.00181
|
|
MAP4K1
|
mitogen-activated protein kinase kinase kinase kinase 1
|
2.92726
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.48127
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.47806
|
|
HDGFL3
|
HDGF like 3
|
2.46881
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.44554
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.4331
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.33441
|
|
EVL
|
Enah/Vasp-like
|
2.25327
|
|
RPL39L
|
ribosomal protein L39-like
|
2.20969
|
|
LCN2
|
lipocalin 2
|
2.18265
|
|
PMP22
|
peripheral myelin protein 22
|
2.17872
|
|
ZNF589
|
zinc finger protein 589
|
2.12898
|
|
RIPOR2
|
RHO family interacting cell polarization regulator 2
|
2.12858
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.12358
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.05541
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
CCNB2
|
cyclin B2
|
-5.79611
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-5.23178
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-5.22056
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-5.10005
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.86849
|
|
DNM1L
|
dynamin 1-like
|
-4.84668
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.83317
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.79152
|
|
CDC20
|
cell division cycle 20
|
-4.63551
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.84395
|
|
TP53BP2
|
tumor protein p53 binding protein 2
|
-3.55517
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.79624
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.56081
|
|
VAT1
|
vesicle amine transport 1
|
-2.5537
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.4461
|
|
SNX11
|
sorting nexin 11
|
-2.37526
|
|
COX6B1
|
cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)
|
-2.33959
|
|
AOC1
|
amine oxidase, copper containing 1
|
-2.24936
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.20788
|
|
RUVBL2
|
RuvB-like AAA ATPase 2
|
-2.19421
|
|
ACTR1A
|
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
|
-2.19044
|
|
TLR4
|
toll-like receptor 4
|
-2.11957
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.03531
|
