CRCGN009_HEPG2_24H:N07 Gene Set
Genes
47 genes differentially expressed following the CRCGN009_HEPG2_24H:N07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
7.12813
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
6.2947
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.9533
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.61833
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.58917
|
|
TGFBR2
|
transforming growth factor, beta receptor II (70/80kDa)
|
3.42773
|
|
CBR3
|
carbonyl reductase 3
|
3.3921
|
|
LCN2
|
lipocalin 2
|
3.33333
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
3.1829
|
|
CYCS
|
cytochrome c, somatic
|
3.11787
|
|
MYLK
|
myosin light chain kinase
|
3.0658
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.00273
|
|
NUCB2
|
nucleobindin 2
|
2.84823
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
2.72787
|
|
PIP4K2B
|
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
|
2.59403
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
2.57467
|
|
PLS1
|
plastin 1
|
2.50293
|
|
HOXA10
|
homeobox A10
|
2.44013
|
|
ZNF589
|
zinc finger protein 589
|
2.24136
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
2.1143
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.09867
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.02833
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-4.7349
|
|
ZNF586
|
zinc finger protein 586
|
-4.72147
|
|
CDC25B
|
cell division cycle 25B
|
-4.44943
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.69843
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.6006
|
|
CD320
|
CD320 molecule
|
-3.40007
|
|
CDC20
|
cell division cycle 20
|
-3.33333
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-3.24862
|
|
COG7
|
component of oligomeric golgi complex 7
|
-3.20527
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.20453
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.1698
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.15417
|
|
CCNB1
|
cyclin B1
|
-3.1434
|
|
LDHD
|
lactate dehydrogenase D
|
-3.02793
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.9393
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.80553
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.62562
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.27714
|
|
ALPK1
|
alpha-kinase 1
|
-2.20473
|
|
CD58
|
CD58 molecule
|
-2.14936
|
|
REL
|
v-rel avian reticuloendotheliosis viral oncogene homolog
|
-2.1436
|
|
ABHD18
|
abhydrolase domain containing 18
|
-2.12143
|
|
DAPP1
|
dual adaptor of phosphotyrosine and 3-phosphoinositides
|
-2.11503
|
|
IL10RB
|
interleukin 10 receptor, beta
|
-2.08203
|
|
TMBIM4
|
transmembrane BAX inhibitor motif containing 4
|
-2.0135
|
