CRCGN009_HEPG2_24H:N09 Gene Set
Genes
42 genes differentially expressed following the CRCGN009_HEPG2_24H:N09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ATP11B
|
ATPase, class VI, type 11B
|
4.65812
|
|
MYLK
|
myosin light chain kinase
|
4.27143
|
|
E2F2
|
E2F transcription factor 2
|
4.26073
|
|
UBQLN2
|
ubiquilin 2
|
4.02418
|
|
PTK2
|
protein tyrosine kinase 2
|
3.87307
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
3.86341
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.79123
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
3.47359
|
|
CBR3
|
carbonyl reductase 3
|
3.19985
|
|
LCN2
|
lipocalin 2
|
3.08928
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.9855
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.95338
|
|
CEP57
|
centrosomal protein 57kDa
|
2.9114
|
|
TEX10
|
testis expressed 10
|
2.78474
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.56443
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.51042
|
|
CCNF
|
cyclin F
|
2.46011
|
|
CCNE2
|
cyclin E2
|
2.26964
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
2.2585
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.21273
|
|
GATAD2A
|
GATA zinc finger domain containing 2A
|
2.20305
|
|
CDKN2D
|
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
|
2.19845
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.12577
|
|
CETN3
|
centrin, EF-hand protein, 3
|
2.08017
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-5.84985
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-4.43723
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.34329
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-4.1994
|
|
CCNB1
|
cyclin B1
|
-4.09083
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.77542
|
|
TLR4
|
toll-like receptor 4
|
-3.71544
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.66059
|
|
CAB39
|
calcium binding protein 39
|
-3.54067
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.24325
|
|
CCNB2
|
cyclin B2
|
-3.20835
|
|
CSK
|
c-src tyrosine kinase
|
-3.03394
|
|
ILK
|
integrin-linked kinase
|
-2.70267
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.59794
|
|
GLOD4
|
glyoxalase domain containing 4
|
-2.52483
|
|
HMG20B
|
high mobility group 20B
|
-2.39147
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.38709
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.13247
|
