CRCGN009_HEPG2_24H:N10 Gene Set
Genes
49 genes differentially expressed following the CRCGN009_HEPG2_24H:N10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
7.76887
|
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
7.1467
|
|
LAGE3
|
L antigen family, member 3
|
5.23874
|
|
MSRA
|
methionine sulfoxide reductase A
|
4.71331
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.69033
|
|
EAPP
|
E2F-associated phosphoprotein
|
4.65672
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
4.53088
|
|
ATP11B
|
ATPase, class VI, type 11B
|
4.43371
|
|
STK10
|
serine/threonine kinase 10
|
4.39603
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.19184
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.81229
|
|
PRKCH
|
protein kinase C, eta
|
3.70121
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.5708
|
|
MCM3
|
minichromosome maintenance complex component 3
|
3.39123
|
|
STXBP2
|
syntaxin binding protein 2
|
3.11032
|
|
MAP7
|
microtubule-associated protein 7
|
3.09333
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.02545
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.82518
|
|
FZD7
|
frizzled class receptor 7
|
2.70645
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.67147
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.5596
|
|
CHEK2
|
checkpoint kinase 2
|
2.54082
|
|
TBP
|
TATA box binding protein
|
2.41319
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.33929
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.28928
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.12151
|
|
WDR7
|
WD repeat domain 7
|
2.05352
|
|
MKNK1
|
MAP kinase interacting serine/threonine kinase 1
|
2.02605
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-8.72234
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-8.68781
|
|
ADI1
|
acireductone dioxygenase 1
|
-6.1481
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.47064
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-5.0611
|
|
TSPAN4
|
tetraspanin 4
|
-4.25955
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.91849
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.87201
|
|
LDHD
|
lactate dehydrogenase D
|
-3.79088
|
|
CCNB1
|
cyclin B1
|
-3.78934
|
|
CCNB2
|
cyclin B2
|
-3.74566
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.64366
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-3.45912
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.23731
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.19276
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.15281
|
|
WASHC4
|
WASH complex subunit 4
|
-2.99832
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.94239
|
|
GET1
|
guided entry of tail-anchored proteins factor 1
|
-2.34219
|
|
EGF
|
epidermal growth factor
|
-2.05912
|
|
SOAT2
|
sterol O-acyltransferase 2
|
-2.04377
|
