| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | o-nitrotoluene 2.52 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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49 genes differentially expressed following the CRCGN009_HEPG2_24H:N11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STK10 | serine/threonine kinase 10 | 4.95288 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 4.90663 |
| E2F2 | E2F transcription factor 2 | 4.67189 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.58495 |
| ABHD4 | abhydrolase domain containing 4 | 4.27652 |
| MYLK | myosin light chain kinase | 4.20637 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.12541 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.9456 |
| MAP7 | microtubule-associated protein 7 | 3.50298 |
| DIPK1A | divergent protein kinase domain 1A | 3.43206 |
| ICAM1 | intercellular adhesion molecule 1 | 3.22218 |
| PLSCR1 | phospholipid scramblase 1 | 3.0553 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.79933 |
| TRAM2 | translocation associated membrane protein 2 | 2.77141 |
| PNKP | polynucleotide kinase 3'-phosphatase | 2.67431 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.56401 |
| MEST | mesoderm specific transcript | 2.5317 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 | 2.45199 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.41651 |
| TNIP1 | TNFAIP3 interacting protein 1 | 2.33321 |
| CHMP6 | charged multivesicular body protein 6 | 2.2637 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.22884 |
| UBQLN2 | ubiquilin 2 | 2.20352 |
| BAX | BCL2-associated X protein | 2.20327 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.00147 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -6.33669 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -5.82894 |
| LDHD | lactate dehydrogenase D | -5.54617 |
| ZNF586 | zinc finger protein 586 | -5.46923 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 | -5.1429 |
| CDC25B | cell division cycle 25B | -4.85786 |
| VDAC1 | voltage-dependent anion channel 1 | -4.61833 |
| UGDH | UDP-glucose 6-dehydrogenase | -4.43129 |
| ADI1 | acireductone dioxygenase 1 | -3.91654 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.85208 |
| TLR4 | toll-like receptor 4 | -3.39508 |
| GNAS | GNAS complex locus | -3.25583 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -3.20092 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -2.99017 |
| LOC124907782 | dual specificity protein phosphatase 22 | -2.9168 |
| CSK | c-src tyrosine kinase | -2.78507 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.74872 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -2.59637 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.58933 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.56224 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.31217 |
| TRIB3 | tribbles pseudokinase 3 | -2.22243 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.22188 |
| NANOS3 | nanos homolog 3 (Drosophila) | -2.05147 |
