| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | o-nitrotoluene 1.26 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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70 genes differentially expressed following the CRCGN009_HEPG2_24H:N12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 6.01151 |
| GPER1 | G protein-coupled estrogen receptor 1 | 5.36551 |
| NOTCH1 | notch 1 | 5.29411 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 5.02268 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.72692 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.6818 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 4.67982 |
| UBQLN2 | ubiquilin 2 | 4.52832 |
| RPL39L | ribosomal protein L39-like | 4.3822 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.2688 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.21316 |
| SATB1 | SATB homeobox 1 | 4.20133 |
| CBR3 | carbonyl reductase 3 | 4.12716 |
| SQOR | sulfide quinone oxidoreductase | 4.10809 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.10686 |
| CCL2 | chemokine (C-C motif) ligand 2 | 4.04749 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 3.80924 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.58964 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 3.45984 |
| PIP4K2B | phosphatidylinositol-5-phosphate 4-kinase, type II, beta | 3.41812 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 3.32098 |
| PRR15L | proline rich 15-like | 3.18647 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.27718 |
| ZNF589 | zinc finger protein 589 | 2.25574 |
| SPG21 | spastic paraplegia 21 (autosomal recessive, Mast syndrome) | 2.11578 |
| MLPH | melanophilin | 2.10459 |
| ICMT | isoprenylcysteine carboxyl methyltransferase | 2.07402 |
| PLP1 | proteolipid protein 1 | 2.0389 |
| MXRA8 | matrix-remodelling associated 8 | 2.0271 |
| GPR137B | G protein-coupled receptor 137B | 2.01167 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF586 | zinc finger protein 586 | -7.79555 |
| UGDH | UDP-glucose 6-dehydrogenase | -5.01953 |
| TRIB3 | tribbles pseudokinase 3 | -4.88533 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.54591 |
| DSG2 | desmoglein 2 | -4.20469 |
| TLR4 | toll-like receptor 4 | -3.63221 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -3.53959 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.40739 |
| GDF15 | growth differentiation factor 15 | -3.31622 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.28754 |
| HMG20B | high mobility group 20B | -3.22925 |
| SNX11 | sorting nexin 11 | -3.21221 |
| CCNB2 | cyclin B2 | -3.19318 |
| NGRN | neugrin, neurite outgrowth associated | -3.05411 |
| ZNF551 | zinc finger protein 551 | -2.91785 |
| TES | testin LIM domain protein | -2.90045 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -2.79886 |
| ZNF222 | zinc finger protein 222 | -2.7313 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.64798 |
| ZNF587B | zinc finger protein 587B | -2.64453 |
| SOAT2 | sterol O-acyltransferase 2 | -2.60673 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -2.58146 |
| ZNF134 | zinc finger protein 134 | -2.37483 |
| ANXA13 | annexin A13 | -2.34492 |
| ZNF223 | zinc finger protein 223 | -2.26939 |
| ZNF324B | zinc finger protein 324B | -2.23441 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D | -2.18104 |
| STX4 | syntaxin 4 | -2.1681 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A | -2.16151 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) | -2.15192 |
| ZNF227 | zinc finger protein 227 | -2.14735 |
| ANKRD40 | ankyrin repeat domain 40 | -2.12167 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -2.12084 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -2.11615 |
| SMPD3 | sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II) | -2.09964 |
| ZNF8 | zinc finger protein 8 | -2.09295 |
| TLE6 | transducin-like enhancer of split 6 | -2.06805 |
| TMLHE | trimethyllysine hydroxylase, epsilon | -2.05794 |
| ASB7 | ankyrin repeat and SOCS box containing 7 | -2.01842 |
| PALM | paralemmin | -2.01195 |
