CRCGN009_HEPG2_24H:N15 Gene Set
Genes
38 genes differentially expressed following the CRCGN009_HEPG2_24H:N15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
8.14453
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
6.25117
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
6.07992
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
5.01799
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
4.90857
|
|
MOK
|
MOK protein kinase
|
4.69048
|
|
NOTCH1
|
notch 1
|
4.68714
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
4.30426
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.04649
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.45687
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.374
|
|
IDE
|
insulin-degrading enzyme
|
3.03579
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.95055
|
|
MAP7
|
microtubule-associated protein 7
|
2.89418
|
|
STIMATE
|
STIM activating enhancer
|
2.69546
|
|
TEX10
|
testis expressed 10
|
2.15948
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
2.10958
|
|
CHEK2
|
checkpoint kinase 2
|
2.07633
|
|
JADE2
|
jade family PHD finger 2
|
2.03468
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-9.7303
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.64396
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.63677
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-4.31729
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.4767
|
|
CCNB2
|
cyclin B2
|
-3.39475
|
|
EGF
|
epidermal growth factor
|
-3.18184
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.86798
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.61636
|
|
ZNF586
|
zinc finger protein 586
|
-2.50136
|
|
PEG10
|
paternally expressed 10
|
-2.44586
|
|
RPIA
|
ribose 5-phosphate isomerase A
|
-2.439
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.43173
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.18129
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-2.1604
|
|
FAF1
|
Fas (TNFRSF6) associated factor 1
|
-2.09344
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.08814
|
|
CPNE3
|
copine III
|
-2.05995
|
|
NVL
|
nuclear VCP-like
|
-2.03209
|
