CRCGN009_HEPG2_24H:N16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 9-ethyl-9h-carbazol-3-amine hydrochloride 2.53 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

56 genes differentially expressed following the CRCGN009_HEPG2_24H:N16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 7.38185
CBR3 carbonyl reductase 3 6.67389
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 6.17788
UBQLN2 ubiquilin 2 6.15058
E2F2 E2F transcription factor 2 5.52939
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.90662
MYLK myosin light chain kinase 3.83637
RPP38 ribonuclease P/MRP 38kDa subunit 3.25437
BACE2 beta-site APP-cleaving enzyme 2 3.05478
LPAR2 lysophosphatidic acid receptor 2 3.02928
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.94033
LCN2 lipocalin 2 2.88249
ATP11B ATPase, class VI, type 11B 2.86292
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.82428
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.81693
CIAO3 cytosolic iron-sulfur assembly component 3 2.79474
HEBP1 heme binding protein 1 2.75809
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.74868
EPHB2 EPH receptor B2 2.68773
LOC122526780 uncharacterized LOC122526780 2.62182
EVL Enah/Vasp-like 2.5841
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.46983
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.46908
PEX11A peroxisomal biogenesis factor 11 alpha 2.44978
TBXT T-box transcription factor T 2.41845
SNCA synuclein, alpha (non A4 component of amyloid precursor) 2.23212
SPG11 spastic paraplegia 11 (autosomal recessive) 2.22616
HOXA10 homeobox A10 2.19989
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.18734
UCN urocortin 2.15816
PM20D1 peptidase M20 domain containing 1 2.15277
SATB1 SATB homeobox 1 2.11886
HGD homogentisate 1,2-dioxygenase 2.07819
LYRM1 LYR motif containing 1 2.0344
CCL2 chemokine (C-C motif) ligand 2 2.03415
EGF epidermal growth factor 2.02359
LRRC47 leucine rich repeat containing 47 2.00551

decreased expression

Symbol Name Standardized Value
PCNA proliferating cell nuclear antigen -9.66451
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -6.97932
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -6.83347
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -3.88862
TARBP1 TAR (HIV-1) RNA binding protein 1 -3.10452
TXNDC9 thioredoxin domain containing 9 -3.00841
LDHD lactate dehydrogenase D -2.72348
TOMM34 translocase of outer mitochondrial membrane 34 -2.65751
ZDHHC6 zinc finger, DHHC-type containing 6 -2.63985
MAPK13 mitogen-activated protein kinase 13 -2.61752
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -2.53034
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.44486
EIF5 eukaryotic translation initiation factor 5 -2.39172
ZMIZ1 zinc finger, MIZ-type containing 1 -2.37874
YME1L1 YME1-like 1 ATPase -2.27316
MACF1 microtubule-actin crosslinking factor 1 -2.25486
ILK integrin-linked kinase -2.18354
CASP7 caspase 7, apoptosis-related cysteine peptidase -2.18276
TLR4 toll-like receptor 4 -2.13235