| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 9-ethyl-9h-carbazol-3-amine hydrochloride 1.27 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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51 genes differentially expressed following the CRCGN009_HEPG2_24H:N17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| UBQLN2 | ubiquilin 2 | 7.07253 |
| CHMP6 | charged multivesicular body protein 6 | 4.11309 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 4.02342 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 3.83244 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 3.4431 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 3.12677 |
| NOTCH1 | notch 1 | 3.09059 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.99379 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.83512 |
| GSTZ1 | glutathione S-transferase zeta 1 | 2.81748 |
| DIPK1A | divergent protein kinase domain 1A | 2.74315 |
| LOC122526780 | uncharacterized LOC122526780 | 2.63129 |
| JADE2 | jade family PHD finger 2 | 2.46803 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.3896 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 2.33494 |
| MICALL1 | MICAL-like 1 | 2.30711 |
| PRKCH | protein kinase C, eta | 2.20474 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 2.19686 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 2.17286 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 2.15673 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 2.12609 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -7.0108 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -6.54573 |
| GNAS | GNAS complex locus | -5.27029 |
| ZNF586 | zinc finger protein 586 | -4.60583 |
| PEG10 | paternally expressed 10 | -4.56674 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -4.34119 |
| LRPAP1 | low density lipoprotein receptor-related protein associated protein 1 | -4.04975 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.04123 |
| RPIA | ribose 5-phosphate isomerase A | -4.00859 |
| CCDC86 | coiled-coil domain containing 86 | -3.62177 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.39633 |
| EGF | epidermal growth factor | -3.3122 |
| FASTKD5 | FAST kinase domains 5 | -3.23356 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.10286 |
| ZW10 | zw10 kinetochore protein | -3.09209 |
| HYOU1 | hypoxia up-regulated 1 | -2.99382 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -2.9315 |
| PDHX | pyruvate dehydrogenase complex, component X | -2.86337 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -2.82354 |
| RAI14 | retinoic acid induced 14 | -2.78456 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D | -2.57552 |
| ISOC1 | isochorismatase domain containing 1 | -2.52606 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.46155 |
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -2.39525 |
| DNAI1 | dynein, axonemal, intermediate chain 1 | -2.15212 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | -2.10662 |
| VPS51 | vacuolar protein sorting 51 homolog (S. cerevisiae) | -2.08276 |
| CDC50B | cell division cycle 50 P4-ATPase accessory subunit B | -2.07965 |
| HMBOX1 | homeobox containing 1 | -2.06714 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.0423 |
