CRCGN009_HEPG2_24H:N18 Gene Set
Genes
38 genes differentially expressed following the CRCGN009_HEPG2_24H:N18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
8.76283
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
7.3382
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
6.51428
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.09419
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
4.94156
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
4.92571
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.32704
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
4.17285
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
4.0429
|
|
HOXA10
|
homeobox A10
|
3.7529
|
|
CEP57
|
centrosomal protein 57kDa
|
2.87853
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.8669
|
|
MX1
|
MX dynamin-like GTPase 1
|
2.54582
|
|
GPATCH8
|
G patch domain containing 8
|
2.45708
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.44325
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
2.29306
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.12928
|
|
MX2
|
MX dynamin-like GTPase 2
|
2.01656
|
|
IFIT1
|
interferon-induced protein with tetratricopeptide repeats 1
|
2.0136
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-8.71261
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-6.88374
|
|
EGF
|
epidermal growth factor
|
-4.72279
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-4.15748
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.02395
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.86556
|
|
TLR4
|
toll-like receptor 4
|
-3.59283
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.41739
|
|
NISCH
|
nischarin
|
-3.31579
|
|
WASHC4
|
WASH complex subunit 4
|
-3.02557
|
|
TMEM115
|
transmembrane protein 115
|
-2.84401
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.76551
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.68995
|
|
CLPB
|
ClpB homolog, mitochondrial AAA ATPase chaperonin
|
-2.37297
|
|
RGS16
|
regulator of G-protein signaling 16
|
-2.28519
|
|
AUP1
|
ancient ubiquitous protein 1
|
-2.11504
|
|
AMBRA1
|
autophagy/beclin-1 regulator 1
|
-2.10118
|
|
IFRD2
|
interferon-related developmental regulator 2
|
-2.07448
|
|
CHIC2
|
cysteine-rich hydrophobic domain 2
|
-2.01726
|
