CRCGN009_HEPG2_24H:N19 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description auramine-o 39.6 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

638 genes differentially expressed following the CRCGN009_HEPG2_24H:N19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CCDC92 coiled-coil domain containing 92 10.0
CDPF1 cysteine-rich, DPF motif domain containing 1 10.0
INPP1 inositol polyphosphate-1-phosphatase 10.0
CNPY3 canopy FGF signaling regulator 3 9.81501
TIMP2 TIMP metallopeptidase inhibitor 2 9.01589
EVL Enah/Vasp-like 8.40109
TRIB3 tribbles pseudokinase 3 8.18684
SQOR sulfide quinone oxidoreductase 7.32828
LCN2 lipocalin 2 6.66122
HSPA1A heat shock 70kDa protein 1A 6.58245
KIFBP kinesin family binding protein 6.46201
STX1A syntaxin 1A (brain) 6.22534
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 5.90673
ABHD4 abhydrolase domain containing 4 5.78645
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 5.77786
MICALL1 MICAL-like 1 5.76633
IGFBP3 insulin-like growth factor binding protein 3 5.5247
LRP10 low density lipoprotein receptor-related protein 10 5.48301
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 5.35502
NPC1 Niemann-Pick disease, type C1 5.25251
ALAS1 5'-aminolevulinate synthase 1 5.25081
NANOS3 nanos homolog 3 (Drosophila) 4.90806
LOXL1 lysyl oxidase-like 1 4.89923
MVP major vault protein 4.85482
CASC3 cancer susceptibility candidate 3 4.79943
TERF2IP telomeric repeat binding factor 2, interacting protein 4.67989
FOSL1 FOS-like antigen 1 4.64587
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 4.63278
PPARG peroxisome proliferator-activated receptor gamma 4.61752
PRAF2 PRA1 domain family, member 2 4.55221
DDIT4 DNA-damage-inducible transcript 4 4.48649
MTERF3 mitochondrial transcription termination factor 3 4.46476
SNX7 sorting nexin 7 4.41196
UBQLN2 ubiquilin 2 4.4075
H2BC12 H2B clustered histone 12 4.36847
GPC1 glypican 1 4.32193
NR1H2 nuclear receptor subfamily 1, group H, member 2 4.18098
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 4.17452
CIAO3 cytosolic iron-sulfur assembly component 3 4.12277
H2BC21 H2B clustered histone 21 4.09295
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 4.07303
TXNRD1 thioredoxin reductase 1 4.06777
SARS1 seryl-tRNA synthetase 1 4.02392
ATP11B ATPase, class VI, type 11B 4.01727
GFOD1 glucose-fructose oxidoreductase domain containing 1 3.89751
SQSTM1 sequestosome 1 3.88101
LSR lipolysis stimulated lipoprotein receptor 3.86965
E2F2 E2F transcription factor 2 3.84977
GHR growth hormone receptor 3.8484
VAT1 vesicle amine transport 1 3.8242
H2AC6 H2A clustered histone 6 3.76183
GFPT1 glutamine--fructose-6-phosphate transaminase 1 3.75356
POLD4 polymerase (DNA-directed), delta 4, accessory subunit 3.73909
STAP2 signal transducing adaptor family member 2 3.69362
TBPL1 TBP-like 1 3.64943
CSNK1E casein kinase 1, epsilon 3.64827
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 3.64283
ANKRD10 ankyrin repeat domain 10 3.56259
TSC22D3 TSC22 domain family, member 3 3.5595
BACE2 beta-site APP-cleaving enzyme 2 3.53442
AARS1 alanyl-tRNA synthetase 1 3.52753
NUP58 nucleoporin 58 3.48377
RAB11FIP1 RAB11 family interacting protein 1 (class I) 3.44753
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.43872
PRR15L proline rich 15-like 3.35058
ZFP36 ZFP36 ring finger protein 3.34379
GARS1 glycyl-tRNA synthetase 1 3.32487
ADGRG1 adhesion G protein-coupled receptor G1 3.27614
BIRC2 baculoviral IAP repeat containing 2 3.21378
MEST mesoderm specific transcript 3.18806
STXBP1 syntaxin binding protein 1 3.15074
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 3.1471
TOMM34 translocase of outer mitochondrial membrane 34 3.1414
YIPF3 Yip1 domain family, member 3 3.12309
NOTCH1 notch 1 3.08966
CLIP4 CAP-GLY domain containing linker protein family, member 4 3.06081
IER3 immediate early response 3 3.05202
TRIM8 tripartite motif containing 8 3.04455
EPHB2 EPH receptor B2 3.03409
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2 3.02085
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1 3.01945
CTSL cathepsin L 3.01242
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator 3.01195
GTPBP2 GTP binding protein 2 2.97565
TESK1 testis-specific kinase 1 2.96775
ATF4 activating transcription factor 4 2.95866
KLHL21 kelch-like family member 21 2.95643
C2CD2L C2CD2-like 2.95049
DDB2 damage-specific DNA binding protein 2, 48kDa 2.93847
NPDC1 neural proliferation, differentiation and control, 1 2.93237
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 2.92873
TP53 tumor protein p53 2.91684
TGFB1I1 transforming growth factor beta 1 induced transcript 1 2.90769
DGKB diacylglycerol kinase, beta 90kDa 2.87832
JOSD1 Josephin domain containing 1 2.85825
MBOAT7 membrane bound O-acyltransferase domain containing 7 2.85741
EIF3L eukaryotic translation initiation factor 3, subunit L 2.84776
RUSC2 RUN and SH3 domain containing 2 2.84631
LOC128125814 uncharacterized LOC128125814 2.81936
GIPC1 GIPC PDZ domain containing family, member 1 2.80585
LARP6 La ribonucleoprotein domain family, member 6 2.79844
VNN1 vanin 1 2.79428
ZNF358 zinc finger protein 358 2.78756
STN1 STN1 subunit of CST complex 2.78401
HMG20B high mobility group 20B 2.75494
EGR1 early growth response 1 2.74989
RGS2 regulator of G-protein signaling 2 2.74791
HKDC1 hexokinase domain containing 1 2.73906
YARS1 tyrosyl-tRNA synthetase 1 2.73705
EPS8L3 EPS8-like 3 2.7295
DGKI diacylglycerol kinase, iota 2.7257
H2AC25 H2A clustered histone 25 2.72466
EIF3D eukaryotic translation initiation factor 3, subunit D 2.7215
LGALS4 lectin, galactoside-binding, soluble, 4 2.71481
IL4R interleukin 4 receptor 2.71474
TES testin LIM domain protein 2.6981
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2.68574
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) 2.67784
GADD45A growth arrest and DNA-damage-inducible, alpha 2.67733
TAOK3 TAO kinase 3 2.67337
MYC v-myc avian myelocytomatosis viral oncogene homolog 2.66824
PRKCH protein kinase C, eta 2.65514
UPP1 uridine phosphorylase 1 2.65327
PTPN12 protein tyrosine phosphatase, non-receptor type 12 2.6523
TOR4A torsin family 4, member A 2.65033
CAMTA2 calmodulin binding transcription activator 2 2.64761
NPTX2 neuronal pentraxin II 2.64745
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 2.64553
SMAD3 SMAD family member 3 2.63189
HOXA2 homeobox A2 2.63059
PPIE peptidylprolyl isomerase E (cyclophilin E) 2.62546
IL1B interleukin 1, beta 2.60174
CAPN1 calpain 1, (mu/I) large subunit 2.59961
SYF2 SYF2 pre-mRNA-splicing factor 2.58897
TRIM13 tripartite motif containing 13 2.58035
TBC1D15 TBC1 domain family, member 15 2.57943
YIPF4 Yip1 domain family, member 4 2.57816
POLR3D polymerase (RNA) III (DNA directed) polypeptide D, 44kDa 2.57797
PTPRK protein tyrosine phosphatase, receptor type, K 2.57305
CIRSR corepressor of RBPJ and splicing regulator 2.57245
AHNAK2 AHNAK nucleoprotein 2 2.56661
TCEA2 transcription elongation factor A (SII), 2 2.56158
DSE dermatan sulfate epimerase 2.5512
ASCC1 activating signal cointegrator 1 complex subunit 1 2.5438
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.53516
UNC13A unc-13 homolog A (C. elegans) 2.51915
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor 2.51833
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) 2.51496
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 2.51073
MAST2 microtubule associated serine/threonine kinase 2 2.50949
TRAPPC6A trafficking protein particle complex 6A 2.50486
MTFR1 mitochondrial fission regulator 1 2.50401
UNC5B unc-5 homolog B (C. elegans) 2.50351
RHBDF1 rhomboid 5 homolog 1 (Drosophila) 2.48961
MAPK12 mitogen-activated protein kinase 12 2.47702
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 2.46785
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2 2.46456
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12 2.45018
RAB11FIP2 RAB11 family interacting protein 2 (class I) 2.44996
NCF2 neutrophil cytosolic factor 2 2.43878
CNTNAP3B contactin associated protein-like 3B 2.43736
RIOK3 RIO kinase 3 2.43702
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 2.43594
ATOSB atos homolog B 2.435
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.43378
MAD2L1BP MAD2L1 binding protein 2.43187
IMPG2 interphotoreceptor matrix proteoglycan 2 2.42593
CDK7 cyclin-dependent kinase 7 2.42059
TWF2 twinfilin actin binding protein 2 2.41725
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3 2.41337
IFRD1 interferon-related developmental regulator 1 2.4128
CYTH2 cytohesin 2 2.39898
BCO1 beta-carotene oxygenase 1 2.39589
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 2.39501
WDR13 WD repeat domain 13 2.39401
CSRNP2 cysteine-serine-rich nuclear protein 2 2.38129
RAI14 retinoic acid induced 14 2.38068
RAP1GAP RAP1 GTPase activating protein 2.36837
PLK3 polo-like kinase 3 2.36584
SIX3 SIX homeobox 3 2.36326
TREM2 triggering receptor expressed on myeloid cells 2 2.36201
MAPK10 mitogen-activated protein kinase 10 2.35044
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa 2.34796
MTMR6 myotubularin related protein 6 2.33037
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) 2.32907
PLA2G2F phospholipase A2, group IIF 2.32724
SLC26A4 solute carrier family 26 (anion exchanger), member 4 2.32088
PCDHB11 protocadherin beta 11 2.31934
RB1CC1 RB1-inducible coiled-coil 1 2.31929
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase) 2.31754
GTF2IRD1 GTF2I repeat domain containing 1 2.31752
ST18 suppression of tumorigenicity 18, zinc finger 2.31395
KYAT3 kynurenine aminotransferase 3 2.31074
HPSE heparanase 2.31018
HEYL hes-related family bHLH transcription factor with YRPW motif-like 2.31013
PPARD peroxisome proliferator-activated receptor delta 2.30546
SMIM40 small integral membrane protein 40 2.29841
CLK3 CDC-like kinase 3 2.29648
CYCS cytochrome c, somatic 2.29526
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 2.29501
BRSK2 BR serine/threonine kinase 2 2.29031
NDST3 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3 2.28843
HMGA1 high mobility group AT-hook 1 2.28198
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 2.28176
TP53BP2 tumor protein p53 binding protein 2 2.27508
ZBTB17 zinc finger and BTB domain containing 17 2.27394
SOX4 SRY (sex determining region Y)-box 4 2.26444
RIN3 Ras and Rab interactor 3 2.26413
CGRRF1 cell growth regulator with ring finger domain 1 2.26075
CAMKV CaM kinase-like vesicle-associated 2.2569
SRC SRC proto-oncogene, non-receptor tyrosine kinase 2.25563
RRAGC Ras-related GTP binding C 2.24698
SUN2 Sad1 and UNC84 domain containing 2 2.24199
LMTK2 lemur tyrosine kinase 2 2.23962
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 2.23568
NT5M 5',3'-nucleotidase, mitochondrial 2.22597
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 2.22421
FOXD1 forkhead box D1 2.21814
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) 2.21741
SARM1 sterile alpha and TIR motif containing 1 2.2172
C5AR1 complement component 5a receptor 1 2.21365
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F 2.20205
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma 2.20096
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 2.19422
STX3 syntaxin 3 2.18625
PILRA paired immunoglobin-like type 2 receptor alpha 2.18534
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3 2.1853
KLK10 kallikrein-related peptidase 10 2.18248
PYGB phosphorylase, glycogen; brain 2.18129
ARID5B AT rich interactive domain 5B (MRF1-like) 2.18055
PHKA1 phosphorylase kinase, alpha 1 (muscle) 2.17735
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 2.1767
CD1D CD1d molecule 2.17548
CLEC5A C-type lectin domain family 5, member A 2.17114
HDGFL3 HDGF like 3 2.17112
MRPS10 mitochondrial ribosomal protein S10 2.16814
TMEM140 transmembrane protein 140 2.16785
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 2.16763
RAB21 RAB21, member RAS oncogene family 2.16389
YJU2B YJU2 splicing factor homolog B 2.16358
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 2.15769
CCNB1IP1 cyclin B1 interacting protein 1, E3 ubiquitin protein ligase 2.15669
FEZF2 FEZ family zinc finger 2 2.15551
OLA1 Obg-like ATPase 1 2.15274
H2AC7 H2A clustered histone 7 2.15253
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 2.1507
POLH polymerase (DNA directed), eta 2.1507
ELOVL4 ELOVL fatty acid elongase 4 2.14727
EVI2A ecotropic viral integration site 2A 2.14467
H2BC17 H2B clustered histone 17 2.14446
TMC5 transmembrane channel-like 5 2.14411
VNN2 vanin 2 2.14374
CPEB1 cytoplasmic polyadenylation element binding protein 1 2.14321
TMEM184B transmembrane protein 184B 2.14317
HIC1 hypermethylated in cancer 1 2.13624
MAP7D1 MAP7 domain containing 1 2.13341
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2 2.1327
FABP2 fatty acid binding protein 2, intestinal 2.12958
GRM3 glutamate receptor, metabotropic 3 2.12655
FNTA farnesyltransferase, CAAX box, alpha 2.12445
PVR poliovirus receptor 2.11994
LBP lipopolysaccharide binding protein 2.11759
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 2.11446
KALRN kalirin, RhoGEF kinase 2.113
DUSP14 dual specificity phosphatase 14 2.11245
ULK1 unc-51 like autophagy activating kinase 1 2.11155
RGS10 regulator of G-protein signaling 10 2.11099
ZFAND1 zinc finger, AN1-type domain 1 2.11088
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5 2.1099
NHLH2 nescient helix loop helix 2 2.10691
BCL2L13 BCL2-like 13 (apoptosis facilitator) 2.10297
PTPN14 protein tyrosine phosphatase, non-receptor type 14 2.09971
PPP1R11 protein phosphatase 1, regulatory (inhibitor) subunit 11 2.09805
CMKLR2 chemerin chemokine-like receptor 2 2.09558
MPST mercaptopyruvate sulfurtransferase 2.09487
SLC35F6 solute carrier family 35, member F6 2.09147
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic 2.09022
BUD31 BUD31 homolog (S. cerevisiae) 2.08409
PTCRA pre T-cell antigen receptor alpha 2.08155
BCL2L10 BCL2-like 10 (apoptosis facilitator) 2.07739
EPHB6 EPH receptor B6 2.07639
NUPR1 nuclear protein, transcriptional regulator, 1 2.07608
ADO 2-aminoethanethiol (cysteamine) dioxygenase 2.0757
IFNAR1 interferon (alpha, beta and omega) receptor 1 2.0747
GPR45 G protein-coupled receptor 45 2.06719
SULT1C4 sulfotransferase family, cytosolic, 1C, member 4 2.06625
IL1RAPL1 interleukin 1 receptor accessory protein-like 1 2.06516
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1 2.06437
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family) 2.05977
CTSD cathepsin D 2.05976
CDR2L cerebellar degeneration-related protein 2-like 2.05925
NT5E 5'-nucleotidase, ecto (CD73) 2.05816
SLITRK2 SLIT and NTRK-like family, member 2 2.05596
PRKCD protein kinase C, delta 2.05571
E4F1 E4F transcription factor 1 2.05539
RPP38 ribonuclease P/MRP 38kDa subunit 2.04904
H2BC4 H2B clustered histone 4 2.04482
CCDC68 coiled-coil domain containing 68 2.04334
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11 2.03897
DDX50 DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 2.03812
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 2.03615
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 2.03481
PPP1R16B protein phosphatase 1, regulatory subunit 16B 2.02584
IL10RB interleukin 10 receptor, beta 2.02011
PHF24 PHD finger protein 24 2.01879
NKX3-2 NK3 homeobox 2 2.01866
TMEM19 transmembrane protein 19 2.01461
DUSP6 dual specificity phosphatase 6 2.01415
LRP1B low density lipoprotein receptor-related protein 1B 2.01393
B3GALT2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 2.01141
ROM1 retinal outer segment membrane protein 1 2.01132
MGRN1 mahogunin ring finger 1, E3 ubiquitin protein ligase 2.00985
HLX H2.0-like homeobox 2.00721
AXL AXL receptor tyrosine kinase 2.00698
PHAF1 phagosome assembly factor 1 2.00679
MON1B MON1 secretory trafficking family member B 2.00454
PHLDA3 pleckstrin homology-like domain, family A, member 3 2.004

decreased expression

Symbol Name Standardized Value
PLEKHJ1 pleckstrin homology domain containing, family J member 1 -9.26728
ISOC1 isochorismatase domain containing 1 -9.20074
B4GAT1 beta-1,4-glucuronyltransferase 1 -8.92357
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -7.29141
PCCB propionyl CoA carboxylase, beta polypeptide -7.27872
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -6.99096
ZW10 zw10 kinetochore protein -6.83192
STMN1 stathmin 1 -6.7952
PGAM4 phosphoglycerate mutase family member 4 -6.75841
PARP1 poly (ADP-ribose) polymerase 1 -6.64149
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -6.15932
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa -6.00466
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -5.88159
PROS1 protein S (alpha) -5.70495
PSRC1 proline/serine-rich coiled-coil 1 -5.6632
HMGA2 high mobility group AT-hook 2 -5.54475
CDK1 cyclin-dependent kinase 1 -5.52201
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -5.45332
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -5.40496
INTS3 integrator complex subunit 3 -5.32887
PSMG1 proteasome (prosome, macropain) assembly chaperone 1 -5.31326
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -5.30723
GNAS GNAS complex locus -5.2249
TOP2A topoisomerase (DNA) II alpha 170kDa -5.2001
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial -5.11798
NUP85 nucleoporin 85kDa -5.03966
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) -4.98562
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila) -4.95086
MYCBP MYC binding protein -4.95012
RPIA ribose 5-phosphate isomerase A -4.92317
CCNA2 cyclin A2 -4.84611
NT5DC2 5'-nucleotidase domain containing 2 -4.73133
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.62775
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase -4.58624
AURKB aurora kinase B -4.5838
CD320 CD320 molecule -4.57572
ERBB2 erb-b2 receptor tyrosine kinase 2 -4.45526
SKIC8 SKI8 subunit of superkiller complex -4.45014
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -4.44874
MRPL12 mitochondrial ribosomal protein L12 -4.33171
POLR1A polymerase (RNA) I polypeptide A, 194kDa -4.28068
ADI1 acireductone dioxygenase 1 -4.26676
TFDP1 transcription factor Dp-1 -4.20412
PXMP2 peroxisomal membrane protein 2, 22kDa -4.20348
CDK6 cyclin-dependent kinase 6 -4.18787
CHMP6 charged multivesicular body protein 6 -4.1459
RUVBL1 RuvB-like AAA ATPase 1 -4.0555
CDC20 cell division cycle 20 -4.01848
BLCAP bladder cancer associated protein -3.99574
TSEN2 TSEN2 tRNA splicing endonuclease subunit -3.98114
PRCP prolylcarboxypeptidase (angiotensinase C) -3.93008
BIRC5 baculoviral IAP repeat containing 5 -3.92633
DHX29 DEAH (Asp-Glu-Ala-His) box polypeptide 29 -3.87118
FIRRM FIGNL1 interacting regulator of recombination and mitosis -3.86116
CHEK2 checkpoint kinase 2 -3.8534
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) -3.82378
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -3.75356
TUBB6 tubulin, beta 6 class V -3.74533
HEATR1 HEAT repeat containing 1 -3.73446
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -3.70964
CCNB2 cyclin B2 -3.68375
PLK1 polo-like kinase 1 -3.6726
ZNF274 zinc finger protein 274 -3.66742
MELK maternal embryonic leucine zipper kinase -3.6203
HAT1 histone acetyltransferase 1 -3.61242
PGM1 phosphoglucomutase 1 -3.60539
PPIC peptidylprolyl isomerase C (cyclophilin C) -3.60194
HACD3 3-hydroxyacyl-CoA dehydratase 3 -3.57883
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 -3.53663
RSU1 Ras suppressor protein 1 -3.51852
ACAA1 acetyl-CoA acyltransferase 1 -3.47779
THAP11 THAP domain containing 11 -3.46195
NRIP1 nuclear receptor interacting protein 1 -3.45386
NUCB2 nucleobindin 2 -3.39368
LOC124907782 dual specificity protein phosphatase 22 -3.39282
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -3.3882
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -3.37178
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -3.28633
STAT1 signal transducer and activator of transcription 1, 91kDa -3.2844
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4 -3.26965
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) -3.26692
ARFIP2 ADP-ribosylation factor interacting protein 2 -3.24256
GLRX5 glutaredoxin 5 -3.24133
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha -3.20501
TATDN2 TatD DNase domain containing 2 -3.19182
DERA deoxyribose-phosphate aldolase (putative) -3.18506
ELAVL1 ELAV like RNA binding protein 1 -3.17672
NLRP2B NLR family pyrin domain containing 2B -3.1673
TTC27 tetratricopeptide repeat domain 27 -3.14721
CRELD2 cysteine-rich with EGF-like domains 2 -3.1412
FBXL12 F-box and leucine-rich repeat protein 12 -3.11972
ICAM3 intercellular adhesion molecule 3 -3.11678
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) -3.07472
NCAPG2 non-SMC condensin II complex, subunit G2 -3.05349
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -3.05059
GTF2A2 general transcription factor IIA, 2, 12kDa -3.02874
CDK4 cyclin-dependent kinase 4 -3.02397
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 -3.0032
ELP5 elongator acetyltransferase complex subunit 5 -2.98345
LAGE3 L antigen family, member 3 -2.9792
SRSF2 serine/arginine-rich splicing factor 2 -2.9786
HMOX1 heme oxygenase 1 -2.96706
MLEC malectin -2.95955
GET1 guided entry of tail-anchored proteins factor 1 -2.92136
ASF1B anti-silencing function 1B histone chaperone -2.90426
RPA3 replication protein A3, 14kDa -2.88489
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 -2.88371
EGF epidermal growth factor -2.87393
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3 -2.86905
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) -2.84138
COPS7A COP9 signalosome subunit 7A -2.82866
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) -2.81143
CENPX centromere protein X -2.80779
WEE1 WEE1 G2 checkpoint kinase -2.80462
FBLN5 fibulin 5 -2.79742
PGRMC1 progesterone receptor membrane component 1 -2.79323
TRIP13 thyroid hormone receptor interactor 13 -2.79261
MSH6 mutS homolog 6 -2.79103
MIS18A MIS18 kinetochore protein A -2.78704
LBR lamin B receptor -2.77558
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble -2.76557
MAP3K4 mitogen-activated protein kinase kinase kinase 4 -2.76396
SELE selectin E -2.73177
SLIRP SRA stem-loop interacting RNA binding protein -2.729
COG7 component of oligomeric golgi complex 7 -2.72464
TRAP1 TNF receptor-associated protein 1 -2.72331
TARBP1 TAR (HIV-1) RNA binding protein 1 -2.70907
NASP nuclear autoantigenic sperm protein (histone-binding) -2.70164
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X -2.6971
CDK2 cyclin-dependent kinase 2 -2.69482
GAMT guanidinoacetate N-methyltransferase -2.69296
KIF14 kinesin family member 14 -2.67516
C2CD5 C2 calcium-dependent domain containing 5 -2.67261
ATP7B ATPase, Cu++ transporting, beta polypeptide -2.66882
CDCA3 cell division cycle associated 3 -2.66454
MGST2 microsomal glutathione S-transferase 2 -2.66404
CDKN3 cyclin-dependent kinase inhibitor 3 -2.6545
MRPL19 mitochondrial ribosomal protein L19 -2.65368
NCAPH non-SMC condensin I complex, subunit H -2.64007
PEG10 paternally expressed 10 -2.62283
TOR1AIP2 torsin A interacting protein 2 -2.62202
VKORC1 vitamin K epoxide reductase complex, subunit 1 -2.6165
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -2.61634
ERH enhancer of rudimentary homolog (Drosophila) -2.61597
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) -2.61306
LIME1 Lck interacting transmembrane adaptor 1 -2.61292
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) -2.61038
OIP5 Opa interacting protein 5 -2.60758
AURKA aurora kinase A -2.60659
TMEM9B TMEM9 domain family, member B -2.6035
NNT nicotinamide nucleotide transhydrogenase -2.589
SCARB1 scavenger receptor class B, member 1 -2.58738
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa -2.58198
MCM10 minichromosome maintenance complex component 10 -2.57645
ANAPC1 anaphase promoting complex subunit 1 -2.56753
DCPS decapping enzyme, scavenger -2.55692
CASP3 caspase 3, apoptosis-related cysteine peptidase -2.5509
POP5 processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae) -2.54034
PAGR1 PAXIP1 associated glutamate-rich protein 1 -2.53946
NENF neudesin neurotrophic factor -2.52819
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa -2.5231
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit -2.52294
PIMREG PICALM interacting mitotic regulator -2.52053
TBC1D10C TBC1 domain family, member 10C -2.51141
PLS1 plastin 1 -2.50698
RPN1 ribophorin I -2.49937
PARN poly(A)-specific ribonuclease -2.49644
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 -2.49198
SACM1L SAC1 suppressor of actin mutations 1-like (yeast) -2.48995
DCK deoxycytidine kinase -2.47853
AKAP8 A kinase (PRKA) anchor protein 8 -2.46891
NUP210 nucleoporin 210kDa -2.46457
GPD1L glycerol-3-phosphate dehydrogenase 1-like -2.46177
SYNE2 spectrin repeat containing, nuclear envelope 2 -2.46157
PEPD peptidase D -2.45819
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae) -2.45311
RNASE7 ribonuclease, RNase A family, 7 -2.44957
EMC9 ER membrane protein complex subunit 9 -2.44947
QPRT quinolinate phosphoribosyltransferase -2.44442
SRSF3 serine/arginine-rich splicing factor 3 -2.4436
PFN1 profilin 1 -2.42961
MYH10 myosin, heavy chain 10, non-muscle -2.42662
CTSC cathepsin C -2.42112
HMGN3 high mobility group nucleosomal binding domain 3 -2.40294
NELFCD negative elongation factor complex member C/D -2.40258
TPM1 tropomyosin 1 (alpha) -2.39831
NDUFB3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 3, 12kDa -2.38517
PRUNE1 prune exopolyphosphatase 1 -2.37914
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) -2.37399
HNRNPM heterogeneous nuclear ribonucleoprotein M -2.37375
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa -2.36558
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 -2.35373
PRRC1 proline-rich coiled-coil 1 -2.35039
TENT5C terminal nucleotidyltransferase 5C -2.34757
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -2.34179
MRPL23 mitochondrial ribosomal protein L23 -2.33631
CCS copper chaperone for superoxide dismutase -2.3354
HADH hydroxyacyl-CoA dehydrogenase -2.33157
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8 -2.30977
PTTG1 pituitary tumor-transforming 1 -2.30749
NUP43 nucleoporin 43kDa -2.30467
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 -2.30152
LAP3 leucine aminopeptidase 3 -2.30057
PEBP1 phosphatidylethanolamine binding protein 1 -2.30038
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -2.2934
KIF15 kinesin family member 15 -2.28932
TMX1 thioredoxin-related transmembrane protein 1 -2.27784
LMNB1 lamin B1 -2.27605
NDUFB6 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa -2.27452
LYRM1 LYR motif containing 1 -2.27422
TMCO1 transmembrane and coiled-coil domains 1 -2.27395
GCSH glycine cleavage system protein H (aminomethyl carrier) -2.26956
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 -2.26194
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) -2.25972
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) -2.25778
BLMH bleomycin hydrolase -2.25518
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) -2.25492
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 -2.2522
RBM14-RBM4 RBM14-RBM4 readthrough -2.25046
NDUFS6 NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) -2.23894
KIF4A kinesin family member 4A -2.2389
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast) -2.23186
NUP107 nucleoporin 107kDa -2.22863
DNAAF2 dynein, axonemal, assembly factor 2 -2.22412
KDM3A lysine (K)-specific demethylase 3A -2.2203
TCEAL4 transcription elongation factor A (SII)-like 4 -2.21856
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -2.21519
UBL5 ubiquitin-like 5 -2.21441
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -2.2132
CTSV cathepsin V -2.21293
LDHC lactate dehydrogenase C -2.20665
TUBA1B tubulin, alpha 1b -2.20255
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.19993
IFT81 intraflagellar transport 81 -2.19875
MNAT1 MNAT CDK-activating kinase assembly factor 1 -2.19123
RMI1 RecQ mediated genome instability 1 -2.19062
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -2.1867
SDF2L1 stromal cell-derived factor 2-like 1 -2.18495
SRSF7 serine/arginine-rich splicing factor 7 -2.18336
CPNE3 copine III -2.17438
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -2.17362
SLC2A4RG SLC2A4 regulator -2.1665
GCH1 GTP cyclohydrolase 1 -2.16585
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 -2.1623
UBP1 upstream binding protein 1 (LBP-1a) -2.15972
NUP62 nucleoporin 62kDa -2.1595
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 -2.15943
TENT5A terminal nucleotidyltransferase 5A -2.15932
GINS2 GINS complex subunit 2 (Psf2 homolog) -2.15925
SHCBP1 SHC SH2-domain binding protein 1 -2.1534
PDIA5 protein disulfide isomerase family A, member 5 -2.14952
NPC2 Niemann-Pick disease, type C2 -2.14438
CBR1 carbonyl reductase 1 -2.14112
CCDC15 coiled-coil domain containing 15 -2.14076
XPO1 exportin 1 -2.13816
NIPSNAP1 nipsnap homolog 1 (C. elegans) -2.13806
ZWINT ZW10 interacting kinetochore protein -2.13642
USP6NL USP6 N-terminal like -2.1328
PFAS phosphoribosylformylglycinamidine synthase -2.13039
RAD51AP1 RAD51 associated protein 1 -2.12934
SNRPF small nuclear ribonucleoprotein polypeptide F -2.12862
ASF1A anti-silencing function 1A histone chaperone -2.1267
PUF60 poly-U binding splicing factor 60KDa -2.12665
PDZK1 PDZ domain containing 1 -2.12264
PPP4C protein phosphatase 4, catalytic subunit -2.11879
UBE2N ubiquitin-conjugating enzyme E2N -2.11775
GPS1 G protein pathway suppressor 1 -2.11578
AGMAT agmatine ureohydrolase (agmatinase) -2.11355
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -2.11309
PRDX5 peroxiredoxin 5 -2.11234
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit -2.10859
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -2.1047
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle) -2.09925
DEXI Dexi homolog (mouse) -2.09795
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 -2.09675
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -2.09318
BOLA2B bolA family member 2B -2.09129
SNRNP25 small nuclear ribonucleoprotein 25kDa (U11/U12) -2.08522
DCPH1 damage control phosphatase 1 -2.08403
DUT deoxyuridine triphosphatase -2.08392
QDPR quinoid dihydropteridine reductase -2.08146
PRPF4 pre-mRNA processing factor 4 -2.07809
STIMATE STIM activating enhancer -2.07588
DCP2 decapping mRNA 2 -2.07515
ORC6 origin recognition complex, subunit 6 -2.07355
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa -2.07282
KANSL1 KAT8 regulatory NSL complex subunit 1 -2.0721
GEMIN6 gem (nuclear organelle) associated protein 6 -2.07115
PPA2 pyrophosphatase (inorganic) 2 -2.06812
DHRS2 dehydrogenase/reductase (SDR family) member 2 -2.06478
ANKRD17 ankyrin repeat domain 17 -2.0633
NEK4 NIMA-related kinase 4 -2.0602
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit -2.05969
SRSF1 serine/arginine-rich splicing factor 1 -2.05658
AHCY adenosylhomocysteinase -2.05467
SHMT1 serine hydroxymethyltransferase 1 (soluble) -2.05436
FUS FUS RNA binding protein -2.05134
FANCI Fanconi anemia, complementation group I -2.04941
MRGBP MRG/MORF4L binding protein -2.04866
NME4 NME/NM23 nucleoside diphosphate kinase 4 -2.04857
ATOX1 antioxidant 1 copper chaperone -2.04827
FAM174C family with sequence similarity 174 member C -2.04675
RUVBL2 RuvB-like AAA ATPase 2 -2.04344
COX17 COX17 cytochrome c oxidase copper chaperone -2.04329
SLC30A10 solute carrier family 30, member 10 -2.03964
GINS1 GINS complex subunit 1 (Psf1 homolog) -2.03933
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa -2.03817
ANXA7 annexin A7 -2.03759
PPIH peptidylprolyl isomerase H (cyclophilin H) -2.03241
HSPE1 heat shock 10kDa protein 1 -2.03084
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme -2.02754
TRIM52 tripartite motif containing 52 -2.02158
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) -2.01882
MTCH2 mitochondrial carrier 2 -2.01856
C1QTNF3 C1q and tumor necrosis factor related protein 3 -2.01789
BCL7C B-cell CLL/lymphoma 7C -2.0148
CLU clusterin -2.01309
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae) -2.00915
CTNNBL1 catenin, beta like 1 -2.00629
SIRT3 sirtuin 3 -2.0019
RBM25 RNA binding motif protein 25 -2.00183