CRCGN009_HEPG2_24H:O07 Gene Set
Genes
42 genes differentially expressed following the CRCGN009_HEPG2_24H:O07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STIMATE
|
STIM activating enhancer
|
8.39416
|
|
LCN2
|
lipocalin 2
|
7.60921
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
7.50819
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
6.47446
|
|
CYCS
|
cytochrome c, somatic
|
4.53617
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.09276
|
|
MAP7
|
microtubule-associated protein 7
|
4.08065
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.02876
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.64481
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.39938
|
|
TPD52L2
|
tumor protein D52-like 2
|
3.25272
|
|
PRKCH
|
protein kinase C, eta
|
3.19886
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.14897
|
|
HOXA10
|
homeobox A10
|
3.07207
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.97315
|
|
GPATCH8
|
G patch domain containing 8
|
2.73161
|
|
SOCS2
|
suppressor of cytokine signaling 2
|
2.71858
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.64619
|
|
TXNRD1
|
thioredoxin reductase 1
|
2.26313
|
|
SKIC8
|
SKI8 subunit of superkiller complex
|
2.11857
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
2.09112
|
|
TLR4
|
toll-like receptor 4
|
2.04196
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GOLT1B
|
golgi transport 1B
|
-4.56496
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-4.47944
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.46978
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.36854
|
|
RAI14
|
retinoic acid induced 14
|
-4.36534
|
|
LDHD
|
lactate dehydrogenase D
|
-3.87694
|
|
PEG10
|
paternally expressed 10
|
-3.68483
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-3.32805
|
|
EGF
|
epidermal growth factor
|
-3.318
|
|
CCNB1
|
cyclin B1
|
-3.12184
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-3.01475
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.01372
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.92361
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.69349
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.5233
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.47994
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.36277
|
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6
|
-2.26469
|
|
HOXC11
|
homeobox C11
|
-2.03074
|
|
USP6NL
|
USP6 N-terminal like
|
-2.0111
|
