CRCGN009_HEPG2_24H:O08 Gene Set
Genes
50 genes differentially expressed following the CRCGN009_HEPG2_24H:O08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABHD6
|
abhydrolase domain containing 6
|
5.17297
|
|
CYCS
|
cytochrome c, somatic
|
4.67504
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
4.01413
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.98044
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.86397
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.83285
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.78306
|
|
MYLK
|
myosin light chain kinase
|
3.65199
|
|
CBR3
|
carbonyl reductase 3
|
3.37509
|
|
CCNF
|
cyclin F
|
3.29607
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.28079
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.20074
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.84454
|
|
PLS1
|
plastin 1
|
2.73074
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.59448
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.59147
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.44023
|
|
STXBP2
|
syntaxin binding protein 2
|
2.39912
|
|
CHN1
|
chimerin 1
|
2.37171
|
|
HOXA10
|
homeobox A10
|
2.32813
|
|
EVL
|
Enah/Vasp-like
|
2.32217
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.25712
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.22839
|
|
HEBP1
|
heme binding protein 1
|
2.17559
|
|
ZNF589
|
zinc finger protein 589
|
2.08634
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.07705
|
|
TMED9
|
transmembrane emp24 protein transport domain containing 9
|
2.05042
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-5.4153
|
|
CCNB2
|
cyclin B2
|
-4.85494
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.99078
|
|
VAT1
|
vesicle amine transport 1
|
-3.77067
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-3.76381
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-3.74966
|
|
CSK
|
c-src tyrosine kinase
|
-3.60298
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-3.30185
|
|
EGF
|
epidermal growth factor
|
-3.29849
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-3.11523
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.83898
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.81049
|
|
TUBB6
|
tubulin, beta 6 class V
|
-2.65941
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.64246
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.63013
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-2.46216
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.40818
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.39153
|
|
GTF2H3
|
general transcription factor IIH, polypeptide 3, 34kDa
|
-2.30696
|
|
ACAA1
|
acetyl-CoA acyltransferase 1
|
-2.19329
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.18869
|
|
FAH
|
fumarylacetoacetate hydrolase (fumarylacetoacetase)
|
-2.07896
|
