CRCGN009_HEPG2_24H:O09 Gene Set
Genes
50 genes differentially expressed following the CRCGN009_HEPG2_24H:O09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
9.25392
|
|
MAP7
|
microtubule-associated protein 7
|
7.03966
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
5.598
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.94314
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
4.56625
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.45627
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
4.27164
|
|
NOTCH1
|
notch 1
|
4.16981
|
|
CYCS
|
cytochrome c, somatic
|
3.58404
|
|
E2F2
|
E2F transcription factor 2
|
3.47744
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.36801
|
|
SATB1
|
SATB homeobox 1
|
3.36355
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.93854
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
2.91402
|
|
FPGS
|
folylpolyglutamate synthase
|
2.87745
|
|
CHEK2
|
checkpoint kinase 2
|
2.82158
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
2.62472
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.61025
|
|
TPD52L2
|
tumor protein D52-like 2
|
2.53075
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.32764
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.32254
|
|
EVL
|
Enah/Vasp-like
|
2.23002
|
|
GPATCH8
|
G patch domain containing 8
|
2.21466
|
|
HEBP1
|
heme binding protein 1
|
2.17725
|
|
VGLL3
|
vestigial-like family member 3
|
2.14404
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.12017
|
|
TUBB4B
|
tubulin, beta 4B class IVb
|
2.07347
|
|
UBQLN2
|
ubiquilin 2
|
2.05943
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-7.0593
|
|
ZW10
|
zw10 kinetochore protein
|
-5.22663
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-5.01206
|
|
LDHD
|
lactate dehydrogenase D
|
-4.86654
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.5385
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
-4.36489
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-4.3412
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.3279
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.20999
|
|
TRIB3
|
tribbles pseudokinase 3
|
-3.93822
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-3.5628
|
|
GNAS
|
GNAS complex locus
|
-3.34144
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.90684
|
|
PSMB10
|
proteasome (prosome, macropain) subunit, beta type, 10
|
-2.89336
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.48808
|
|
COG2
|
component of oligomeric golgi complex 2
|
-2.43169
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.20992
|
|
SEZ6L2
|
seizure related 6 homolog (mouse)-like 2
|
-2.19307
|
|
CTNNBL1
|
catenin, beta like 1
|
-2.18631
|
|
HMG20B
|
high mobility group 20B
|
-2.12376
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.09737
|
|
MGP
|
matrix Gla protein
|
-2.02159
|
