| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | monochloroacetic acid 4.85 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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89 genes differentially expressed following the CRCGN009_HEPG2_24H:O10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CHMP6 | charged multivesicular body protein 6 | 10.0 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 8.30706 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 8.08103 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 6.74238 |
| MAP7 | microtubule-associated protein 7 | 5.97222 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.91716 |
| ADRB2 | adrenoceptor beta 2, surface | 4.69245 |
| PRR15L | proline rich 15-like | 4.12117 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit | 3.68146 |
| MYLK | myosin light chain kinase | 3.37843 |
| PFKL | phosphofructokinase, liver | 3.32549 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 3.21196 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 3.19298 |
| HOXA10 | homeobox A10 | 3.19297 |
| UBQLN2 | ubiquilin 2 | 2.774 |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 | 2.73304 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 2.71631 |
| CHN1 | chimerin 1 | 2.6605 |
| MRPL30 | mitochondrial ribosomal protein L30 | 2.57229 |
| NENF | neudesin neurotrophic factor | 2.51009 |
| CCNA1 | cyclin A1 | 2.47279 |
| NPIPB6 | nuclear pore complex interacting protein family, member B6 | 2.4601 |
| PLSCR3 | phospholipid scramblase 3 | 2.35297 |
| WDR4 | WD repeat domain 4 | 2.34292 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 | 2.31665 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.27835 |
| CTC1 | CTS telomere maintenance complex component 1 | 2.2059 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | 2.19712 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | 2.16246 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | 2.15732 |
| RBMX | RNA binding motif protein, X-linked | 2.11943 |
| RHOT2 | ras homolog family member T2 | 2.11892 |
| ALDH18A1 | aldehyde dehydrogenase 18 family, member A1 | 2.09817 |
| CDK10 | cyclin-dependent kinase 10 | 2.08268 |
| VGLL4 | vestigial-like family member 4 | 2.08177 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 2.0485 |
| TLR2 | toll-like receptor 2 | 2.03539 |
| PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 2.03484 |
| HOXA7 | homeobox A7 | 2.02309 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.01969 |
| NAE1 | NEDD8 activating enzyme E1 subunit 1 | 2.00592 |
| ULBP2 | UL16 binding protein 2 | 2.00515 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -8.14609 |
| PEG10 | paternally expressed 10 | -7.90942 |
| GNAS | GNAS complex locus | -7.55694 |
| FAIM | Fas apoptotic inhibitory molecule | -5.07605 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit | -5.03404 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.64054 |
| EGF | epidermal growth factor | -3.9393 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -3.90564 |
| LOC124907782 | dual specificity protein phosphatase 22 | -3.64678 |
| GOLT1B | golgi transport 1B | -3.64175 |
| CCNB2 | cyclin B2 | -3.52546 |
| VAT1 | vesicle amine transport 1 | -3.49887 |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble | -3.49439 |
| ADI1 | acireductone dioxygenase 1 | -3.36936 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.21427 |
| ZNF586 | zinc finger protein 586 | -3.15594 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.13898 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.90068 |
| H1-5 | H1.5 linker histone, cluster member | -2.78939 |
| RNF167 | ring finger protein 167 | -2.6373 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 | -2.63337 |
| NEUROD1 | neuronal differentiation 1 | -2.58892 |
| TNS2 | tensin 2 | -2.58808 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.49142 |
| LIF | leukemia inhibitory factor | -2.45265 |
| CSAD | cysteine sulfinic acid decarboxylase | -2.43083 |
| PRND | prion protein 2 (dublet) | -2.37625 |
| LYPD1 | LY6/PLAUR domain containing 1 | -2.33209 |
| MBNL3 | muscleblind-like splicing regulator 3 | -2.28165 |
| BEAN1 | brain expressed, associated with NEDD4, 1 | -2.27846 |
| TLCD3A | TLC domain containing 3A | -2.24052 |
| SHCBP1L | SHC SH2-domain binding protein 1-like | -2.2243 |
| ACLY | ATP citrate lyase | -2.22369 |
| PDZD2 | PDZ domain containing 2 | -2.20619 |
| RPS15A | ribosomal protein S15a | -2.19839 |
| GSG1 | germ cell associated 1 | -2.18391 |
| H2BC14 | H2B clustered histone 14 | -2.16947 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -2.15449 |
| RNF139 | ring finger protein 139 | -2.09935 |
| NDUFS1 | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | -2.08503 |
| ZNF623 | zinc finger protein 623 | -2.07223 |
| CCNB1 | cyclin B1 | -2.07138 |
| CUZD1 | CUB and zona pellucida-like domains 1 | -2.04015 |
| FUZ | fuzzy planar cell polarity protein | -2.01663 |
| CD70 | CD70 molecule | -2.01426 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | -2.01315 |
| AURKA | aurora kinase A | -2.00049 |
