CRCGN009_HEPG2_24H:O11 Gene Set
Genes
56 genes differentially expressed following the CRCGN009_HEPG2_24H:O11 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
9.05132
|
|
NOTCH1
|
notch 1
|
5.14483
|
|
STK10
|
serine/threonine kinase 10
|
4.94183
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
4.77599
|
|
MOK
|
MOK protein kinase
|
4.7564
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.62224
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
4.5369
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.48644
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.26812
|
|
MCOLN1
|
mucolipin 1
|
4.07975
|
|
STIMATE
|
STIM activating enhancer
|
3.98548
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
3.87478
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
3.80432
|
|
ABHD4
|
abhydrolase domain containing 4
|
3.70592
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.7838
|
|
VGLL4
|
vestigial-like family member 4
|
2.71695
|
|
WDR7
|
WD repeat domain 7
|
2.57579
|
|
TBC1D31
|
TBC1 domain family, member 31
|
2.53778
|
|
KIF5C
|
kinesin family member 5C
|
2.52644
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.48149
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.39663
|
|
HPRT1
|
hypoxanthine phosphoribosyltransferase 1
|
2.30348
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.16525
|
|
EVL
|
Enah/Vasp-like
|
2.14226
|
|
HYOU1
|
hypoxia up-regulated 1
|
2.1306
|
|
GATA2
|
GATA binding protein 2
|
2.10953
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.06879
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-7.3691
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-6.58469
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-5.52735
|
|
ZNF586
|
zinc finger protein 586
|
-5.01317
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-4.96542
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.90577
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.80161
|
|
CDC20
|
cell division cycle 20
|
-4.79147
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.69159
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-4.49968
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-4.24044
|
|
ENOPH1
|
enolase-phosphatase 1
|
-4.13021
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-4.09581
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.04604
|
|
LDHD
|
lactate dehydrogenase D
|
-3.99891
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.78132
|
|
HMG20B
|
high mobility group 20B
|
-3.49567
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.40295
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-3.05975
|
|
HEATR1
|
HEAT repeat containing 1
|
-2.9969
|
|
GNAS
|
GNAS complex locus
|
-2.8938
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.80049
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.63066
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
-2.24504
|
|
WASHC4
|
WASH complex subunit 4
|
-2.24039
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.11733
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.09515
|
|
FBP1
|
fructose-1,6-bisphosphatase 1
|
-2.06896
|
|
CAB39
|
calcium binding protein 39
|
-2.06357
|
