CRCGN009_HEPG2_24H:O13 Gene Set
Genes
49 genes differentially expressed following the CRCGN009_HEPG2_24H:O13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
6.91249
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.65545
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
5.02755
|
|
NOTCH1
|
notch 1
|
4.49785
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.86583
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.70808
|
|
MOK
|
MOK protein kinase
|
3.34514
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.85133
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.83736
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.70027
|
|
FZD7
|
frizzled class receptor 7
|
2.60729
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.59336
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.52892
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.48459
|
|
UBQLN2
|
ubiquilin 2
|
2.47928
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.44365
|
|
FPGS
|
folylpolyglutamate synthase
|
2.34305
|
|
CYCS
|
cytochrome c, somatic
|
2.17821
|
|
HOXA10
|
homeobox A10
|
2.16352
|
|
TOR4A
|
torsin family 4, member A
|
2.105
|
|
CORO1A
|
coronin, actin binding protein, 1A
|
2.06628
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.02506
|
|
CEP57
|
centrosomal protein 57kDa
|
2.01647
|
|
TBC1D9B
|
TBC1 domain family, member 9B (with GRAM domain)
|
2.00341
|
|
SFTPB
|
surfactant protein B
|
2.00152
|
|
PTK2
|
protein tyrosine kinase 2
|
2.00042
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-6.21422
|
|
CCNB2
|
cyclin B2
|
-5.55772
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-5.09623
|
|
THAP11
|
THAP domain containing 11
|
-4.5503
|
|
LDHD
|
lactate dehydrogenase D
|
-4.22849
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.21944
|
|
EGF
|
epidermal growth factor
|
-3.2024
|
|
HYOU1
|
hypoxia up-regulated 1
|
-3.13677
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.8784
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.85435
|
|
SESN1
|
sestrin 1
|
-2.73023
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.58649
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.4954
|
|
CCNH
|
cyclin H
|
-2.44649
|
|
DNM1L
|
dynamin 1-like
|
-2.38337
|
|
STAMBP
|
STAM binding protein
|
-2.31829
|
|
TLR4
|
toll-like receptor 4
|
-2.24899
|
|
RNF167
|
ring finger protein 167
|
-2.17607
|
|
PARD6A
|
par-6 family cell polarity regulator alpha
|
-2.14099
|
|
WDR70
|
WD repeat domain 70
|
-2.14098
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.14077
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.14003
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-2.06254
|
