CRCGN009_HEPG2_24H:O15 Gene Set
Genes
51 genes differentially expressed following the CRCGN009_HEPG2_24H:O15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.33216
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
4.31203
|
|
SQOR
|
sulfide quinone oxidoreductase
|
3.93558
|
|
MYLK
|
myosin light chain kinase
|
3.82643
|
|
LCN2
|
lipocalin 2
|
3.59882
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.59608
|
|
ABHD4
|
abhydrolase domain containing 4
|
3.57799
|
|
E2F2
|
E2F transcription factor 2
|
3.49715
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
3.25765
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.13233
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.02438
|
|
UBE2A
|
ubiquitin-conjugating enzyme E2A
|
2.70673
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.61107
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.58788
|
|
ADAM10
|
ADAM metallopeptidase domain 10
|
2.48868
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.44867
|
|
AGL
|
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
|
2.43372
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.366
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.17345
|
|
KLHL9
|
kelch-like family member 9
|
2.13916
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.12607
|
|
GATA3
|
GATA binding protein 3
|
2.10001
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.08279
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.05134
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-7.53516
|
|
GNAS
|
GNAS complex locus
|
-7.52018
|
|
CCNB2
|
cyclin B2
|
-4.88486
|
|
VAT1
|
vesicle amine transport 1
|
-4.06215
|
|
TUBB6
|
tubulin, beta 6 class V
|
-3.88667
|
|
TNFRSF21
|
tumor necrosis factor receptor superfamily, member 21
|
-3.84988
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.79029
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.71235
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.49585
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-3.46527
|
|
TSPAN4
|
tetraspanin 4
|
-3.36752
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.21547
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.09964
|
|
TLR4
|
toll-like receptor 4
|
-2.74173
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.72034
|
|
PEG10
|
paternally expressed 10
|
-2.70671
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.5846
|
|
MTA1
|
metastasis associated 1
|
-2.58457
|
|
CTSD
|
cathepsin D
|
-2.55557
|
|
ATP11B
|
ATPase, class VI, type 11B
|
-2.53388
|
|
LDHD
|
lactate dehydrogenase D
|
-2.38463
|
|
ZNF586
|
zinc finger protein 586
|
-2.27654
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.19843
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.1372
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.12985
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.06391
|
|
RBM15B
|
RNA binding motif protein 15B
|
-2.01177
|
