CRCGN009_HEPG2_24H:O16 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description (1e)-2-methyl-1-({[(methylamino)carbonyl]oxy}imino)-2-(methylsulfanyl)propane 2.63 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

46 genes differentially expressed following the CRCGN009_HEPG2_24H:O16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
STAP2 signal transducing adaptor family member 2 6.74723
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 4.67099
CHMP6 charged multivesicular body protein 6 4.50683
HEBP1 heme binding protein 1 4.48384
CBR3 carbonyl reductase 3 4.16739
LCN2 lipocalin 2 3.11619
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.96793
STIMATE STIM activating enhancer 2.67452
ABHD6 abhydrolase domain containing 6 2.66995
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 2.62635
DYNLT3 dynein, light chain, Tctex-type 3 2.61073
CCNF cyclin F 2.41654
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 2.38758
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.38407
RALGDS ral guanine nucleotide dissociation stimulator 2.34767
IKZF1 IKAROS family zinc finger 1 (Ikaros) 2.28807
CEP57 centrosomal protein 57kDa 2.27997
MAP7 microtubule-associated protein 7 2.14556
ADRB2 adrenoceptor beta 2, surface 2.10926
SNX7 sorting nexin 7 2.04578
EVL Enah/Vasp-like 2.03278

decreased expression

Symbol Name Standardized Value
ZMIZ1 zinc finger, MIZ-type containing 1 -5.33753
CASP7 caspase 7, apoptosis-related cysteine peptidase -4.96661
CCDC86 coiled-coil domain containing 86 -4.95604
RPIA ribose 5-phosphate isomerase A -4.73661
TLR4 toll-like receptor 4 -4.55601
DNM1L dynamin 1-like -4.49485
ADI1 acireductone dioxygenase 1 -4.36941
PRPF4 pre-mRNA processing factor 4 -4.11745
MAPK13 mitogen-activated protein kinase 13 -3.59899
B4GAT1 beta-1,4-glucuronyltransferase 1 -3.16262
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -2.86772
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.85023
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 -2.74942
CCNB1 cyclin B1 -2.73662
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -2.64721
CDC25B cell division cycle 25B -2.51474
FBXO7 F-box protein 7 -2.44875
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -2.43646
NRIP1 nuclear receptor interacting protein 1 -2.41602
GOLT1B golgi transport 1B -2.41338
PRPF19 pre-mRNA processing factor 19 -2.37183
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 -2.27026
LY6G6F-LY6G6D LY6G6F-LY6G6D readthrough -2.2538
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.1072
SESN1 sestrin 1 -2.00535