CRCGN009_HEPG2_24H:O17 Gene Set
Genes
44 genes differentially expressed following the CRCGN009_HEPG2_24H:O17 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
8.19515
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
5.28882
|
|
JADE2
|
jade family PHD finger 2
|
4.70685
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.58569
|
|
CHMP6
|
charged multivesicular body protein 6
|
4.1566
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.57256
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.42587
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
3.06955
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.78088
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.55634
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.50228
|
|
PFKL
|
phosphofructokinase, liver
|
2.46504
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.46458
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.38197
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.37584
|
|
RAMP1
|
receptor (G protein-coupled) activity modifying protein 1
|
2.32218
|
|
PCNT
|
pericentrin
|
2.22079
|
|
GLDC
|
glycine dehydrogenase (decarboxylating)
|
2.21171
|
|
HAMP
|
hepcidin antimicrobial peptide
|
2.03887
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ADI1
|
acireductone dioxygenase 1
|
-8.27456
|
|
LDHD
|
lactate dehydrogenase D
|
-5.84581
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.80374
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.81473
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.32926
|
|
TRIB3
|
tribbles pseudokinase 3
|
-4.26622
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-4.1259
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.79972
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.48061
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.1278
|
|
TLR4
|
toll-like receptor 4
|
-3.09902
|
|
ZNF586
|
zinc finger protein 586
|
-3.0572
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.99221
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-2.98566
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.89545
|
|
HMG20B
|
high mobility group 20B
|
-2.87528
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.74229
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.55087
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.453
|
|
SUPV3L1
|
suppressor of var1, 3-like 1 (S. cerevisiae)
|
-2.3826
|
|
GREM1
|
gremlin 1, DAN family BMP antagonist
|
-2.13546
|
|
DYSF
|
dysferlin
|
-2.13506
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.12945
|
|
SLC6A3
|
solute carrier family 6 (neurotransmitter transporter), member 3
|
-2.08836
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.0524
|
