CRCGN009_HEPG2_24H:O18 Gene Set
Genes
52 genes differentially expressed following the CRCGN009_HEPG2_24H:O18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
6.27067
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.00673
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.28653
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
3.28187
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.26573
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.17127
|
|
GPATCH8
|
G patch domain containing 8
|
3.13797
|
|
STIMATE
|
STIM activating enhancer
|
3.11673
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.05893
|
|
MOK
|
MOK protein kinase
|
3.0227
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.01193
|
|
PMM2
|
phosphomannomutase 2
|
2.97503
|
|
LCN2
|
lipocalin 2
|
2.9644
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.8943
|
|
NOTCH1
|
notch 1
|
2.7528
|
|
EPHA3
|
EPH receptor A3
|
2.65821
|
|
NUP133
|
nucleoporin 133kDa
|
2.6524
|
|
KIF20A
|
kinesin family member 20A
|
2.6347
|
|
CYCS
|
cytochrome c, somatic
|
2.43057
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.33283
|
|
SFTPB
|
surfactant protein B
|
2.32242
|
|
MAP7
|
microtubule-associated protein 7
|
2.10509
|
|
FPGS
|
folylpolyglutamate synthase
|
2.09687
|
|
DHDDS
|
dehydrodolichyl diphosphate synthase
|
2.07398
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.03172
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.0237
|
|
ASXL2
|
additional sex combs like transcriptional regulator 2
|
2.01773
|
|
CCNF
|
cyclin F
|
2.0048
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.44183
|
|
LDHD
|
lactate dehydrogenase D
|
-6.3481
|
|
PCNA
|
proliferating cell nuclear antigen
|
-6.13007
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-5.64907
|
|
CCNB2
|
cyclin B2
|
-4.89407
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.92063
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-3.63367
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.59743
|
|
B4GAT1
|
beta-1,4-glucuronyltransferase 1
|
-3.57667
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.4724
|
|
NLRP2B
|
NLR family pyrin domain containing 2B
|
-3.31703
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.12197
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-3.05575
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.03863
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-3.02707
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.96155
|
|
PUF60
|
poly-U binding splicing factor 60KDa
|
-2.9484
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-2.79997
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.59824
|
|
GNAS
|
GNAS complex locus
|
-2.47342
|
|
NUP93
|
nucleoporin 93kDa
|
-2.3403
|
|
HMG20B
|
high mobility group 20B
|
-2.22723
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-2.09453
|
|
SCRIB
|
scribbled planar cell polarity protein
|
-2.02723
|
