| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2-[(1,1,2,2-tetrachloroethyl)sulfanyl]-3a,4,7,7a-tetrahydro-1h-isoindole-1,3(2h)-dione 2.6 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
55 genes differentially expressed following the CRCGN009_HEPG2_24H:O22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 4.23362 |
| GPER1 | G protein-coupled estrogen receptor 1 | 4.19761 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 3.95348 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.91477 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 3.79464 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 3.46005 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 3.41288 |
| INPP1 | inositol polyphosphate-1-phosphatase | 3.26439 |
| KIFBP | kinesin family binding protein | 3.25643 |
| IDE | insulin-degrading enzyme | 3.23431 |
| LCN2 | lipocalin 2 | 3.21513 |
| STIMATE | STIM activating enhancer | 3.16335 |
| LPAR2 | lysophosphatidic acid receptor 2 | 3.15526 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 3.11498 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 3.09742 |
| CNPY3 | canopy FGF signaling regulator 3 | 3.0534 |
| LAGE3 | L antigen family, member 3 | 2.95521 |
| CHMP6 | charged multivesicular body protein 6 | 2.88369 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.69002 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.5517 |
| CCP110 | centriolar coiled coil protein 110kDa | 2.48338 |
| FPGS | folylpolyglutamate synthase | 2.45557 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 2.43284 |
| MYLK | myosin light chain kinase | 2.29026 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 2.22013 |
| MAP7 | microtubule-associated protein 7 | 2.16732 |
| TUBB6 | tubulin, beta 6 class V | 2.10317 |
| ACOT9 | acyl-CoA thioesterase 9 | 2.03073 |
| IER3 | immediate early response 3 | 2.01895 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -6.77924 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.98747 |
| FGFR4 | fibroblast growth factor receptor 4 | -5.5708 |
| TLR4 | toll-like receptor 4 | -5.19377 |
| CCNB2 | cyclin B2 | -4.95786 |
| CSK | c-src tyrosine kinase | -4.39131 |
| CCDC86 | coiled-coil domain containing 86 | -4.05767 |
| TCTN1 | tectonic family member 1 | -4.04214 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.53729 |
| CDC20 | cell division cycle 20 | -3.47278 |
| ADI1 | acireductone dioxygenase 1 | -3.31832 |
| FASTKD5 | FAST kinase domains 5 | -3.02793 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | -2.94302 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.92008 |
| PEG10 | paternally expressed 10 | -2.78192 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.7401 |
| DNM1L | dynamin 1-like | -2.62487 |
| GNAS | GNAS complex locus | -2.58823 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.55081 |
| RNF167 | ring finger protein 167 | -2.52792 |
| ACAA1 | acetyl-CoA acyltransferase 1 | -2.51537 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.23107 |
| BIRC2 | baculoviral IAP repeat containing 2 | -2.14186 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) | -2.10362 |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein | -2.10247 |
| ANKRD46 | ankyrin repeat domain 46 | -2.03515 |
