CRCGN009_HEPG2_24H:O23 Gene Set
Genes
50 genes differentially expressed following the CRCGN009_HEPG2_24H:O23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
STK10
|
serine/threonine kinase 10
|
6.95774
|
|
LCN2
|
lipocalin 2
|
6.25778
|
|
PLS1
|
plastin 1
|
3.84389
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.6789
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
3.57055
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.38524
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.27852
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.2645
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.25771
|
|
JADE2
|
jade family PHD finger 2
|
3.25468
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
3.25166
|
|
STIMATE
|
STIM activating enhancer
|
3.18265
|
|
MYLK
|
myosin light chain kinase
|
3.17335
|
|
DENND2D
|
DENN/MADD domain containing 2D
|
2.86311
|
|
UBQLN2
|
ubiquilin 2
|
2.82804
|
|
MOK
|
MOK protein kinase
|
2.73536
|
|
CHEK2
|
checkpoint kinase 2
|
2.21882
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
2.20838
|
|
EPN2
|
epsin 2
|
2.19622
|
|
FPGS
|
folylpolyglutamate synthase
|
2.14585
|
|
TAC4
|
tachykinin 4 (hemokinin)
|
2.13936
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.09957
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.06929
|
|
CEP57
|
centrosomal protein 57kDa
|
2.01912
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.00718
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.8161
|
|
TLR4
|
toll-like receptor 4
|
-5.46145
|
|
ZNF586
|
zinc finger protein 586
|
-5.3233
|
|
PEG10
|
paternally expressed 10
|
-4.73709
|
|
NT5DC2
|
5'-nucleotidase domain containing 2
|
-4.24897
|
|
HMG20B
|
high mobility group 20B
|
-3.93739
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.68127
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.66991
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.51167
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.43284
|
|
HACD3
|
3-hydroxyacyl-CoA dehydratase 3
|
-3.24171
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.1261
|
|
LDHD
|
lactate dehydrogenase D
|
-3.09262
|
|
GOLT1B
|
golgi transport 1B
|
-2.76541
|
|
CDC20
|
cell division cycle 20
|
-2.56067
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.55247
|
|
CSK
|
c-src tyrosine kinase
|
-2.54611
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.53423
|
|
DDIT4
|
DNA-damage-inducible transcript 4
|
-2.47932
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.47856
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.4087
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.36263
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.33274
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.13964
|
|
BIRC2
|
baculoviral IAP repeat containing 2
|
-2.07404
|
