CRCGN009_HEPG2_24H:O24 Gene Set
Genes
39 genes differentially expressed following the CRCGN009_HEPG2_24H:O24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
5.90423
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.7217
|
|
MAP7
|
microtubule-associated protein 7
|
4.51655
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
3.72845
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.1253
|
|
HEBP1
|
heme binding protein 1
|
2.92514
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
2.91105
|
|
GADD45A
|
growth arrest and DNA-damage-inducible, alpha
|
2.86093
|
|
MAMLD1
|
mastermind-like domain containing 1
|
2.81836
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.70871
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.69476
|
|
FPGS
|
folylpolyglutamate synthase
|
2.5524
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.52
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
2.51624
|
|
PRKCH
|
protein kinase C, eta
|
2.44022
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.3839
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.32576
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.31982
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.29813
|
|
CBR3
|
carbonyl reductase 3
|
2.21132
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.20731
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TRIB3
|
tribbles pseudokinase 3
|
-7.58461
|
|
GNAS
|
GNAS complex locus
|
-4.50047
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-4.27483
|
|
PEG10
|
paternally expressed 10
|
-4.02349
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-4.0015
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.85352
|
|
EGF
|
epidermal growth factor
|
-3.54964
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.4226
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.38305
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.08336
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.06301
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.44612
|
|
TSEN2
|
TSEN2 tRNA splicing endonuclease subunit
|
-2.38882
|
|
CDC20
|
cell division cycle 20
|
-2.27175
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.24982
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.07884
|
|
MATCAP2
|
microtubule associated tyrosine carboxypeptidase 2
|
-2.04814
|
|
MAGEB2
|
melanoma antigen family B2
|
-2.02432
|
