| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sorbic-acid 19.9 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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83 genes differentially expressed following the CRCGN009_HEPG2_24H:P02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 7.67645 |
| RPL39L | ribosomal protein L39-like | 6.84841 |
| CHMP6 | charged multivesicular body protein 6 | 6.71655 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 6.60325 |
| CCNF | cyclin F | 3.86093 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.72113 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 3.6492 |
| PLS1 | plastin 1 | 3.57895 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.43979 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 3.33898 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 3.29342 |
| CORO1A | coronin, actin binding protein, 1A | 3.25528 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 3.23187 |
| E2F2 | E2F transcription factor 2 | 3.22249 |
| NUP133 | nucleoporin 133kDa | 3.09581 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.02133 |
| BTK | Bruton agammaglobulinemia tyrosine kinase | 2.96928 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 2.8183 |
| SHB | Src homology 2 domain containing adaptor protein B | 2.81138 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.75105 |
| MEST | mesoderm specific transcript | 2.61481 |
| NT5DC2 | 5'-nucleotidase domain containing 2 | 2.48916 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.46983 |
| NCF4 | neutrophil cytosolic factor 4, 40kDa | 2.4503 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.4313 |
| TPSAB1 | tryptase alpha/beta 1 | 2.40893 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 | 2.284 |
| TRAPPC3 | trafficking protein particle complex 3 | 2.28375 |
| COG2 | component of oligomeric golgi complex 2 | 2.28283 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 2.27844 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 2.25872 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 2.23692 |
| CYCS | cytochrome c, somatic | 2.22142 |
| GATA2 | GATA binding protein 2 | 2.21545 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.14445 |
| HS1BP3 | HCLS1 binding protein 3 | 2.09503 |
| CPA4 | carboxypeptidase A4 | 2.06834 |
| GPS1 | G protein pathway suppressor 1 | 2.03514 |
| CKAP5 | cytoskeleton associated protein 5 | 2.01765 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma | 2.00468 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TLR4 | toll-like receptor 4 | -5.92028 |
| GNAS | GNAS complex locus | -5.19548 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.35719 |
| TOMM34 | translocase of outer mitochondrial membrane 34 | -4.18578 |
| NGRN | neugrin, neurite outgrowth associated | -4.16462 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -4.16228 |
| PRPF4 | pre-mRNA processing factor 4 | -3.78457 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.78181 |
| ZW10 | zw10 kinetochore protein | -3.66946 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.62806 |
| EGF | epidermal growth factor | -3.54394 |
| ADI1 | acireductone dioxygenase 1 | -3.37493 |
| LDHD | lactate dehydrogenase D | -3.21607 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -3.0812 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -3.02329 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.95848 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -2.9151 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -2.87353 |
| PCNA | proliferating cell nuclear antigen | -2.58842 |
| PEG10 | paternally expressed 10 | -2.55384 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.51108 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.51018 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.50576 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.4642 |
| SQOR | sulfide quinone oxidoreductase | -2.41277 |
| HYOU1 | hypoxia up-regulated 1 | -2.39713 |
| DCK | deoxycytidine kinase | -2.32689 |
| MYL9 | myosin, light chain 9, regulatory | -2.32561 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.28296 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -2.26871 |
| CAB39 | calcium binding protein 39 | -2.24446 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.22837 |
| KIFBP | kinesin family binding protein | -2.2188 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | -2.20564 |
| HSPA12A | heat shock 70kDa protein 12A | -2.14355 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -2.12196 |
| CD320 | CD320 molecule | -2.09427 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 | -2.08976 |
| HSPA4 | heat shock 70kDa protein 4 | -2.08202 |
| LRRC41 | leucine rich repeat containing 41 | -2.08107 |
| FAM234B | family with sequence similarity 234 member B | -2.03762 |
| CRYZ | crystallin, zeta (quinone reductase) | -2.0299 |
| THAP11 | THAP domain containing 11 | -2.01912 |
