| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | sorbic-acid 2.49 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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70 genes differentially expressed following the CRCGN009_HEPG2_24H:P05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 5.09677 |
| NOTCH1 | notch 1 | 4.69007 |
| MAP7 | microtubule-associated protein 7 | 4.55491 |
| E2F2 | E2F transcription factor 2 | 4.48094 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.40971 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 4.22024 |
| CYCS | cytochrome c, somatic | 4.11981 |
| CCL2 | chemokine (C-C motif) ligand 2 | 4.11206 |
| HOXA10 | homeobox A10 | 3.9604 |
| CHN1 | chimerin 1 | 3.60272 |
| NOSIP | nitric oxide synthase interacting protein | 3.44603 |
| DYNLT3 | dynein, light chain, Tctex-type 3 | 3.31945 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 3.01355 |
| PDLIM1 | PDZ and LIM domain 1 | 2.97919 |
| GPATCH8 | G patch domain containing 8 | 2.96371 |
| VGLL4 | vestigial-like family member 4 | 2.84522 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 2.84423 |
| PRKCH | protein kinase C, eta | 2.73584 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 2.6795 |
| HOXA10-HOXA9 | HOXA10-HOXA9 readthrough | 2.58727 |
| ADAM10 | ADAM metallopeptidase domain 10 | 2.55988 |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 2.52605 |
| TCTA | T-cell leukemia translocation altered | 2.46318 |
| CCNF | cyclin F | 2.36291 |
| RXYLT1 | ribitol xylosyltransferase 1 | 2.35503 |
| SATB1 | SATB homeobox 1 | 2.23929 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | 2.1869 |
| POLR1A | polymerase (RNA) I polypeptide A, 194kDa | 2.18534 |
| AMDHD2 | amidohydrolase domain containing 2 | 2.10147 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | 2.08369 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa | 2.08089 |
| CAND2 | cullin-associated and neddylation-dissociated 2 (putative) | 2.07586 |
| SLC12A9 | solute carrier family 12, member 9 | 2.05038 |
| LFNG | LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 2.03261 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 | 2.03065 |
| VPS45 | vacuolar protein sorting 45 homolog (S. cerevisiae) | 2.02259 |
| NDUFS7 | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 2.00283 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -6.73163 |
| ZW10 | zw10 kinetochore protein | -6.62466 |
| KDM3A | lysine (K)-specific demethylase 3A | -4.9215 |
| ZNF586 | zinc finger protein 586 | -4.58321 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -3.9999 |
| FASTKD5 | FAST kinase domains 5 | -3.95305 |
| TLR4 | toll-like receptor 4 | -3.77267 |
| PCNA | proliferating cell nuclear antigen | -3.51792 |
| GNAS | GNAS complex locus | -3.25283 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.06588 |
| SNX11 | sorting nexin 11 | -3.06204 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.04309 |
| AURKB | aurora kinase B | -3.02034 |
| TCEAL4 | transcription elongation factor A (SII)-like 4 | -3.01006 |
| PRPF4 | pre-mRNA processing factor 4 | -2.95602 |
| YME1L1 | YME1-like 1 ATPase | -2.91404 |
| RGS2 | regulator of G-protein signaling 2 | -2.79817 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -2.73049 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -2.66456 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.63061 |
| CRYZ | crystallin, zeta (quinone reductase) | -2.4884 |
| HAT1 | histone acetyltransferase 1 | -2.25027 |
| NUP93 | nucleoporin 93kDa | -2.23626 |
| FCHO1 | FCH domain only 1 | -2.16989 |
| SLC35F2 | solute carrier family 35, member F2 | -2.15879 |
| TRIM32 | tripartite motif containing 32 | -2.15361 |
| EAPP | E2F-associated phosphoprotein | -2.1402 |
| DNAAF11 | dynein axonemal assembly factor 11 | -2.0923 |
| MYL9 | myosin, light chain 9, regulatory | -2.06147 |
| MTFR1 | mitochondrial fission regulator 1 | -2.05112 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | -2.04165 |
| ABI1 | abl-interactor 1 | -2.03743 |
| LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.02541 |
