| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dibenzo-p-dioxin 19.8 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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48 genes differentially expressed following the CRCGN009_HEPG2_24H:P08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPATCH8 | G patch domain containing 8 | 4.16704 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 3.56601 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.40733 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 3.30555 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 3.22763 |
| PLS1 | plastin 1 | 3.04053 |
| SFTPB | surfactant protein B | 3.00433 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.7958 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 2.78374 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.60035 |
| NOSIP | nitric oxide synthase interacting protein | 2.57665 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.57301 |
| CCL2 | chemokine (C-C motif) ligand 2 | 2.41914 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 2.39415 |
| TENT4A | terminal nucleotidyltransferase 4A | 2.27415 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 2.2741 |
| PNKP | polynucleotide kinase 3'-phosphatase | 2.26742 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 2.24542 |
| STIMATE | STIM activating enhancer | 2.19263 |
| RHOA | ras homolog family member A | 2.14606 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.12822 |
| TEX10 | testis expressed 10 | 2.02393 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -7.41526 |
| TLR4 | toll-like receptor 4 | -5.4434 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -5.41045 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -5.06024 |
| THAP11 | THAP domain containing 11 | -5.03753 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -4.93122 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.8035 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -4.75205 |
| PRPF4 | pre-mRNA processing factor 4 | -4.36571 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.83863 |
| CCNB2 | cyclin B2 | -3.76529 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -3.5973 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -2.9908 |
| MRPS2 | mitochondrial ribosomal protein S2 | -2.62461 |
| TWF2 | twinfilin actin binding protein 2 | -2.61174 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.60602 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.5694 |
| WASHC4 | WASH complex subunit 4 | -2.47992 |
| ILK | integrin-linked kinase | -2.33528 |
| HMG20B | high mobility group 20B | -2.24113 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.22916 |
| DEF8 | differentially expressed in FDCP 8 homolog (mouse) | -2.20715 |
| ATP6V0B | ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b | -2.18073 |
| HYOU1 | hypoxia up-regulated 1 | -2.15179 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.12149 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 | -2.06589 |
