CRCGN009_HEPG2_24H:P09 Gene Set
Genes
45 genes differentially expressed following the CRCGN009_HEPG2_24H:P09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
7.057
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.62374
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
4.73855
|
|
CBR3
|
carbonyl reductase 3
|
4.15177
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.14616
|
|
STK10
|
serine/threonine kinase 10
|
4.14313
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.76689
|
|
STIMATE
|
STIM activating enhancer
|
3.54374
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
3.26057
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
3.17317
|
|
MOK
|
MOK protein kinase
|
3.15834
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.01585
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.96061
|
|
ZNF589
|
zinc finger protein 589
|
2.81966
|
|
RELB
|
v-rel avian reticuloendotheliosis viral oncogene homolog B
|
2.79169
|
|
MAP3K4
|
mitogen-activated protein kinase kinase kinase 4
|
2.7849
|
|
CYCS
|
cytochrome c, somatic
|
2.77166
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.72436
|
|
LCN2
|
lipocalin 2
|
2.65458
|
|
RRAGA
|
Ras-related GTP binding A
|
2.46011
|
|
DRAP1
|
DR1-associated protein 1 (negative cofactor 2 alpha)
|
2.45245
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.35354
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.24107
|
|
SKIC2
|
SKI2 subunit of superkiller complex
|
2.17983
|
|
VGLL4
|
vestigial-like family member 4
|
2.10697
|
|
TEX10
|
testis expressed 10
|
2.01674
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SCAND1
|
SCAN domain containing 1
|
-4.8631
|
|
GNAS
|
GNAS complex locus
|
-4.38928
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.0305
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-4.02632
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-3.63037
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.58496
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.56256
|
|
HAT1
|
histone acetyltransferase 1
|
-3.19583
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.17348
|
|
CPSF4
|
cleavage and polyadenylation specific factor 4, 30kDa
|
-2.73449
|
|
WASHC4
|
WASH complex subunit 4
|
-2.70428
|
|
CCNB2
|
cyclin B2
|
-2.60542
|
|
CSK
|
c-src tyrosine kinase
|
-2.56395
|
|
LDHD
|
lactate dehydrogenase D
|
-2.47845
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.42871
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.20768
|
|
HMG20B
|
high mobility group 20B
|
-2.17235
|
|
CCNH
|
cyclin H
|
-2.05883
|
|
GLIPR1
|
GLI pathogenesis-related 1
|
-2.05739
|
