CRCGN009_HEPG2_24H:P12 Gene Set
Genes
42 genes differentially expressed following the CRCGN009_HEPG2_24H:P12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
6.73229
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.78641
|
|
UBQLN2
|
ubiquilin 2
|
3.71716
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.622
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.51423
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.46037
|
|
NOTCH1
|
notch 1
|
3.30004
|
|
LCN2
|
lipocalin 2
|
3.24764
|
|
IDE
|
insulin-degrading enzyme
|
3.14468
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.11394
|
|
LYN
|
LYN proto-oncogene, Src family tyrosine kinase
|
3.05258
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.94002
|
|
MAMLD1
|
mastermind-like domain containing 1
|
2.87201
|
|
CYCS
|
cytochrome c, somatic
|
2.72723
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.72452
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.5532
|
|
GATA3
|
GATA binding protein 3
|
2.34543
|
|
EGF
|
epidermal growth factor
|
2.34286
|
|
MEST
|
mesoderm specific transcript
|
2.30394
|
|
ADH5
|
alcohol dehydrogenase 5 (class III), chi polypeptide
|
2.30053
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.26066
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.19299
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.0375
|
|
UFM1
|
ubiquitin-fold modifier 1
|
2.02303
|
|
KDM5A
|
lysine (K)-specific demethylase 5A
|
2.00932
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-7.00195
|
|
ADI1
|
acireductone dioxygenase 1
|
-6.67159
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.74877
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-5.14412
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-4.65204
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.90188
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.89557
|
|
LDHD
|
lactate dehydrogenase D
|
-3.75618
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.48113
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.5826
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-2.55808
|
|
THAP11
|
THAP domain containing 11
|
-2.47609
|
|
ZW10
|
zw10 kinetochore protein
|
-2.26665
|
|
ILK
|
integrin-linked kinase
|
-2.19295
|
|
FHL2
|
four and a half LIM domains 2
|
-2.17816
|
|
CSK
|
c-src tyrosine kinase
|
-2.17489
|
|
SLC5A6
|
solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6
|
-2.0713
|
