| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | spironolactone 0.65 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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59 genes differentially expressed following the CRCGN009_HEPG2_24H:P18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EPHB2 | EPH receptor B2 | 7.84266 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 5.1728 |
| CHMP6 | charged multivesicular body protein 6 | 5.13316 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.52715 |
| DIPK1A | divergent protein kinase domain 1A | 4.23925 |
| MCOLN1 | mucolipin 1 | 4.16553 |
| PEX11A | peroxisomal biogenesis factor 11 alpha | 3.82188 |
| MAP7 | microtubule-associated protein 7 | 3.64933 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.0057 |
| JADE2 | jade family PHD finger 2 | 2.92631 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | 2.78046 |
| DEFA6 | defensin, alpha 6, Paneth cell-specific | 2.67517 |
| KLHL9 | kelch-like family member 9 | 2.58214 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 2.54557 |
| LCN2 | lipocalin 2 | 2.50365 |
| CA5A | carbonic anhydrase VA, mitochondrial | 2.49312 |
| GTF2H1 | general transcription factor IIH, polypeptide 1, 62kDa | 2.43203 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 2.38474 |
| FANCF | Fanconi anemia, complementation group F | 2.34041 |
| CCL24 | chemokine (C-C motif) ligand 24 | 2.27367 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.27156 |
| WASHC3 | WASH complex subunit 3 | 2.27019 |
| PTCD3 | pentatricopeptide repeat domain 3 | 2.2675 |
| RNF34 | ring finger protein 34, E3 ubiquitin protein ligase | 2.25933 |
| TPD52L2 | tumor protein D52-like 2 | 2.2304 |
| HSPA1A | heat shock 70kDa protein 1A | 2.1582 |
| TTC31 | tetratricopeptide repeat domain 31 | 2.14474 |
| CD180 | CD180 molecule | 2.12701 |
| NUCB2 | nucleobindin 2 | 2.12362 |
| KRCC1 | lysine-rich coiled-coil 1 | 2.09904 |
| MATN4 | matrilin 4 | 2.09077 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.06746 |
| GPATCH8 | G patch domain containing 8 | 2.03067 |
| HAGH | hydroxyacylglutathione hydrolase | 2.01427 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | -8.20757 |
| SLC35F2 | solute carrier family 35, member F2 | -5.38051 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -4.36987 |
| CDC20 | cell division cycle 20 | -4.29125 |
| GOLT1B | golgi transport 1B | -4.2547 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.0915 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.79852 |
| TLR4 | toll-like receptor 4 | -3.67891 |
| YME1L1 | YME1-like 1 ATPase | -3.52026 |
| COG2 | component of oligomeric golgi complex 2 | -3.46133 |
| HYOU1 | hypoxia up-regulated 1 | -3.0741 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.97232 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.94479 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.88645 |
| HMG20B | high mobility group 20B | -2.52925 |
| PLA2G15 | phospholipase A2, group XV | -2.52105 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -2.48017 |
| EGF | epidermal growth factor | -2.31366 |
| TWF2 | twinfilin actin binding protein 2 | -2.23443 |
| IFT46 | intraflagellar transport 46 | -2.20976 |
| ZNF226 | zinc finger protein 226 | -2.15048 |
| NUP155 | nucleoporin 155kDa | -2.08787 |
| TGFBR1 | transforming growth factor, beta receptor 1 | -2.06489 |
| GSR | glutathione reductase | -2.05784 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 | -2.04355 |
