| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2,5-dithiobiurea 39.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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61 genes differentially expressed following the CRCGN009_HEPG2_24H:P19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPER1 | G protein-coupled estrogen receptor 1 | 5.35871 |
| LPAR2 | lysophosphatidic acid receptor 2 | 5.13585 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.5538 |
| ABHD6 | abhydrolase domain containing 6 | 4.52902 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 4.29373 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 4.26785 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 4.22609 |
| CBR3 | carbonyl reductase 3 | 4.16378 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 4.13083 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 4.03782 |
| MAP7 | microtubule-associated protein 7 | 3.99455 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 3.69641 |
| CYCS | cytochrome c, somatic | 3.65741 |
| NOTCH1 | notch 1 | 3.48728 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.43176 |
| NOSIP | nitric oxide synthase interacting protein | 3.40205 |
| STXBP2 | syntaxin binding protein 2 | 3.04367 |
| FZD7 | frizzled class receptor 7 | 2.89664 |
| ZNF589 | zinc finger protein 589 | 2.87545 |
| CEP57 | centrosomal protein 57kDa | 2.79758 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.4715 |
| H2BC12 | H2B clustered histone 12 | 2.37256 |
| CHN1 | chimerin 1 | 2.2404 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 2.2234 |
| TWSG1 | twisted gastrulation BMP signaling modulator 1 | 2.21841 |
| GARRE1 | granule associated Rac and RHOG effector 1 | 2.16089 |
| FOXA2 | forkhead box A2 | 2.13157 |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 | 2.08182 |
| MXRA5 | matrix-remodelling associated 5 | 2.04118 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -10.0 |
| VAT1 | vesicle amine transport 1 | -9.14851 |
| PCNA | proliferating cell nuclear antigen | -8.74572 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -5.30202 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.02822 |
| CSK | c-src tyrosine kinase | -4.53362 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -4.1277 |
| WASHC4 | WASH complex subunit 4 | -3.99289 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.91536 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -3.86748 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -3.66228 |
| CCNB2 | cyclin B2 | -3.31619 |
| MTA1 | metastasis associated 1 | -3.1699 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -3.14799 |
| LYPLA1 | lysophospholipase I | -2.98818 |
| DDIT4 | DNA-damage-inducible transcript 4 | -2.87948 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.8188 |
| RAI14 | retinoic acid induced 14 | -2.43707 |
| MSMB | microseminoprotein, beta- | -2.29205 |
| GUCA1B | guanylate cyclase activator 1B (retina) | -2.27608 |
| FAM193B | family with sequence similarity 193, member B | -2.15243 |
| MPC2 | mitochondrial pyruvate carrier 2 | -2.11979 |
| KCND2 | potassium channel, voltage gated Shal related subfamily D, member 2 | -2.11651 |
| PRDM1 | PR domain containing 1, with ZNF domain | -2.09287 |
| HPSE2 | heparanase 2 (inactive) | -2.06787 |
| FSTL4 | follistatin-like 4 | -2.06041 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.05272 |
| CDKL3 | cyclin-dependent kinase-like 3 | -2.04119 |
| MKRN3 | makorin ring finger protein 3 | -2.03835 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 | -2.00817 |
| FAM20B | family with sequence similarity 20, member B | -2.00514 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | -2.00125 |
